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Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling

Neuron(2023)10.1016/j.neuron.2023.08.012Source: DataRank Database

Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling is a research paper published in Neuron (2023). On theSindex it has a DataRank of 0. It has been cited 115 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access115 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 16.46)OA: bronzeTopics (47)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Hyeonwoo Kim ORCID,Mark P. Jedrychowski,Grisilda Bakiasi,Joseph Park ORCID,Jane M. Kruskop

Live enrichment

PubMed:37689059 PMC:PMC10840702 OpenAlex:https://openalex.org/W4386540924

NIA NIH HHS

Grant: RF1 AG048080

NIA NIH HHS

Grant: R56 AG072054

NINDS NIH HHS

Grant: R01 NS117694

NIA NIH HHS

Grant: R21 AG062904

FWCI

16.46

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

bronzeLicense: http://creativecommons.org/licenses/by-nc/4.0/

journalhttp://www.cell.com/article/S0896627323006232/pdf

publisherhttp://www.cell.com/article/S0896627323006232/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0896627323006232?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0896627323006232?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.neuron.2023.08.012

Fields of Study

Adipose Tissue and MetabolismNeuroinflammation and Neurodegeneration MechanismsAdipokines, Inflammation, and Metabolic DiseasesMiceAnimalsNeprilysinFibronectinsDown-RegulationAstrocytesAmyloid beta-PeptidesAlzheimer DiseaseBrain

MeSH Terms

Alzheimer DiseaseAnimalsAstrocytesBrainFibronectinsNeprilysinDown-RegulationAmyloid beta-PeptidesMice

Keywords

FNDC5Downregulation and upregulationNeprilysinMAPK/ERK pathwayFibronectinEndocrinologyReceptorSignal transductionInternal medicineCell biologyChemistryNeuroscienceMedicineCellBiologyEnzymeBiochemistryGeneAlzheimer's diseaseStat3AstrocytesERKAβAmyloid-βIrisinIntegrin Αv/β5

Sustainable Development Goals

SDG 0: Good health and well-being