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Gene delivery using AAV8 in vivo for disease stabilization in a bimodal gene therapy approach for the treatment of ADA-deficient SCID

Molecular Therapy — Methods & Clinical Development(2021)10.1016/j.omtm.2021.02.007Source: DataRank Database

Gene delivery using AAV8 in vivo for disease stabilization in a bimodal gene therapy approach for the treatment of ADA-deficient SCID is a research paper published in Molecular Therapy — Methods & Clinical Development (2021). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.15)OA: goldTopics (40)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Krista Chun ORCID,Danielle N. Clark,Michael L. Kaufman ORCID,Xiangyang Jin,Xiaoyan Wang ORCID

Live enrichment

PubMed:33738330 PMC:PMC7940710 OpenAlex:https://openalex.org/W3129400487

NIAID NIH HHS

Grant: R01 AI074043

NHLBI NIH HHS

Grant: P01 HL073104

NHLBI NIH HHS

Grant: P50 HL054850

National Institutes of Health

Grant: 5P01HL073104-03

Gene Therapy for SCID due to cytiokine receptor defects

National Institutes of Health

Grant: 5R01AI074043-05

In Vivo ADA Gene Delivery for the Treatment of SCID

National Institutes of Health

Grant: 5P50HL054850-07

PILOT PROJECTS

California Institute for Regenerative Medicine

National Institutes of Health

FWCI

0.15

Citation Percentile

0.5%

Citation Trend

2021

2025

goldLicense: cc-by

journalhttp://www.cell.com/article/S232905012100022X/pdf

publisherhttp://www.cell.com/article/S232905012100022X/pdf

journalhttps://doi.org/10.1016/j.omtm.2021.02.007

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33738330

repositoryhttps://doaj.org/article/6f56e2bbb6c145109472570c3a34f96d

Fields of Study

Virus-based gene therapy researchCAR-T cell therapy researchRNA Interference and Gene Delivery0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Adenosine deaminase deficiencyGenetic enhancementAdenosine deaminaseEnzyme replacement therapyBone marrowSevere combined immunodeficiencyViral vectorGene deliveryMedicineVector (molecular biology)HaematopoiesisIn vivoImmunologyHematopoietic stem cell transplantationStem cellBiologyInternal medicineTransplantationDiseaseRecombinant DNAAdenosineGeneGene therapyHematopoietic stem cellslentiviral vectorInborn Errors Of MetabolismAda-scidAav VectorAda-deficiencyQH573-671QH426-470GeneticsOriginal ArticleCytology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being