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Exploring the potential of saponins as adjuvants in lipid-nanoparticle-based mRNA vaccines

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101495Source: DataRank Database

Exploring the potential of saponins as adjuvants in lipid-nanoparticle-based mRNA vaccines is a research paper published in Molecular Therapy — Methods & Clinical Development (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 2.32)OA: goldTopics (28)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Antony Jozić ORCID,Michael Henderson ORCID,Dylan Nelson,Gaurav Sahay ORCID,Yulia Eygeris ORCID

Live enrichment

PubMed:40525124 PMC:PMC12169741 OpenAlex:https://openalex.org/W4410579287

National Institutes of Health

Grant: R01HL146736

National Heart, Lung, and Blood Institute

Grant: R01CA270783-01

National Institutes of Health

Grant: 5R01HL146736-02

Nanoparticles based mRNA delivery for treatment of cystic fibrosis

National Institutes of Health

Grant: 5R01CA270783-02

Mechanistic insights on structure, topology and radiation effects on RNA nanomedicines

Oregon Health and Science University

National Cancer Institute

LAM Therapeutics

Oregon State University

FWCI

2.32

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: CC BY NC ND

journalhttps://doi.org/10.1016/j.omtm.2025.101495

GOLDhttps://doi.org/10.1016/j.omtm.2025.101495

publisherhttps://doi.org/10.1016/j.omtm.2025.101495

publisherhttps://api.elsevier.com/content/article/PII:S2329050125000907?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2329050125000907?httpAccept=text/plain

Fields of Study

Natural product bioactivities and synthesisGlycosylation and Glycoproteins ResearchImmune Response and InflammationMedicineChemistry02 engineering and technology0210 nano-technology

Keywords

Vaccine adjuvantMessenger RNAAdjuvantComputational biologyChemistryPharmacologyBiologyImmunologyBiochemistryGeneGene therapySaponinsVaccineStructure-activity relationshipsLipid NanoparticleMrna DeliveryQH573-671GeneticsOriginal ArticleQH426-470Cytology

Sustainable Development Goals

SDG 0: Zero hunger

Exploring the potential of saponins as adjuvants in lipid-nanoparticle-based mRNA vaccines

FAIR Checklist

Authors (5)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)