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AAV-mediated peripheral scFv's administration to reduce cerebral tau in adult P301S transgenic mice: Mono-vs. combination therapy

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101563Source: DataRank Database

AAV-mediated peripheral scFv's administration to reduce cerebral tau in adult P301S transgenic mice: Mono-vs. combination therapy is a research paper published in Molecular Therapy — Methods & Clinical Development (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (15 grants)Impact (FWCI 0.00)OA: goldTopics (26)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Julia Cicalo,Valeria Vasciaveo ORCID,Laura M. Vecchio ORCID,Joseph Carrión ORCID,Leann Mahadeo

Live enrichment

PubMed:40932994 PMC:PMC12419030 OpenAlex:https://openalex.org/W4413149239

National Institutes of Health

Grant: 5P01AI073693

U.S. Department of Defense

Grant: W81XWH1910759

National Institute on Aging

Grant: 5R01AG061381

Canadian Institutes of Health Research

Grant: FRN168906

Canadian Institutes of Health Research

Grant: FRN166184

Canadian Institutes of Health Research

Grant: 5P01AI102852

NIA NIH HHS

Grant: R01 AG061381

NIAID NIH HHS

Grant: P01 AI102852

NIAID NIH HHS

Grant: P01 AI073693

National Institutes of Health

Grant: 5P01AI102852-05

Cognitive and immune impairments in sepsis survivors

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5P01AI073693-13

Anti NMDA Receptor antibodes in adult brain dysfunction and fetal brain development: lessons from lupus

National Institutes of Health

Grant: 5R01AG061381-03

Vectorized scFv antibodies to treat tau pathology in Alzheimer's disease: enhancing epitope targeting and delivery strategies

Feinstein Institutes for Medical Research

Northwell Health

FWCI

0.00

Citation Percentile

0.2%

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.omtm.2025.101563

publisherhttps://doi.org/10.1016/j.omtm.2025.101563

publisherhttps://api.elsevier.com/content/article/PII:S2329050125001585?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2329050125001585?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40932994

Fields of Study

Alzheimer's disease research and treatmentsS100 Proteins and AnnexinsNuclear Receptors and Signaling03 medical and health sciences0302 clinical medicine

Keywords

Genetically modified mouseTransgenePeripheralMedicinePharmacologyNeuroscienceChemistryInternal medicinePsychologyBiochemistryGene therapyImmunotherapyTauAlzheimer’s diseaseCombination therapyscfvMonotherapy18F-fdg-petEngineered AntibodiesMc1Original Article

Sustainable Development Goals

SDG 0: Zero hunger

AAV-mediated peripheral scFv's administration to reduce cerebral tau in adult P301S transgenic mice: Mono-vs. combination therapy

FAIR Checklist

Authors (12)

Funding (15 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)