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Targeted inhibition of ELANE expression using adenine base editing to treat severe congenital neutropenia

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101626Source: DataRank Database

Targeted inhibition of ELANE expression using adenine base editing to treat severe congenital neutropenia is a research paper published in Molecular Therapy — Methods & Clinical Development (2025). On theSindex it has a DataRank of 0.104. It has been cited 1 time.

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0.104DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 0.89)OA: goldTopics (24)IDs (PubMed, PMC, OpenAlex)Annotations (4)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (18)

Benjamin Dannenmann ORCID,Frank Bernhard ORCID,Masako Monika Kaufmann,Sandra Ammann ORCID,Siarhei Kandabarau ORCID

Live enrichment

PubMed:41438873 PMC:PMC12719991 OpenAlex:https://openalex.org/W4415935127

Deutsche Forschungsgemeinschaft

Grant: CRC1597

NIAID NIH HHS

Grant: R24 AI162637

NIAID NIH HHS

Grant: R24 AI049393

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Foundation for the National Institutes of Health

German Cancer Aid

National Institutes of Health

Albert-Ludwigs-Universität Freiburg

Berlin Institute of Health

Federal Ministry of Education and Research Bonn Office

FWCI

0.89

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.omtm.2025.101626

publisherhttps://doi.org/10.1016/j.omtm.2025.101626

publisherhttps://api.elsevier.com/content/article/PII:S2329050125002219?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2329050125002219?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41438873

Fields of Study

Blood disorders and treatmentsCRISPR and Genetic EngineeringLysosomal Storage Disorders Research0303 health sciences03 medical and health sciences

Keywords

Congenital NeutropeniaNeutrophil extracellular trapsHaematopoiesisNeutrophil elastaseGenome editingStem cellNeutropeniaProgenitor cellRibonucleoproteinGene therapyNeutrophilsHemopoietic Stem CellsSevere Congenital NeutropeniaNetsElaneBone Marrow Failure SyndromePre-leukemiaAdenine Base EditingOriginal Article

Targeted inhibition of ELANE expression using adenine base editing to treat severe congenital neutropenia

FAIR Checklist

DataRank Breakdown

Authors (18)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)