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Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102441Source: DataRank Database

Modeling and correction of protein conformational disease in iPSC-derived neurons through personalized base editing is a research paper published in Molecular Therapy — Nucleic Acids (2024). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 0.80)OA: goldTopics (28)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Nancy Mulaiese,Tanvi Butola ORCID,Qinkun Zhang ORCID,D. I. Каgаn,Qiaoyan Yang ORCID

Live enrichment

PubMed:39877004 PMC:PMC11773622 OpenAlex:https://openalex.org/W4405663816

National Institute of Neurological Disorders and Stroke

Grant: 1R01NS109362-01

Synaptic and Circuit Interactions to Shape Multisensory Processing

National Institute of Neurological Disorders and Stroke

Grant: BRAIN INITIATIVE 1R01NS109994

Indiana Clinical and Translational Sciences Institute

Grant: UL1TR001445

NCI NIH HHS

Grant: P30 CA016086

NIGMS NIH HHS

Grant: T32 GM136542

National Institutes of Health

Grant: 3UL1TR001445-03S1

Clinical and Translational Science Award

National Institutes of Health

Grant: 1T32GM136542-01

Training Program in Cell Biology

National Institutes of Health

Grant: 1R01NS109994-01

Linking Plasticity of Hippocampal Representation across the Single Neuron and Circuit Levels

National Institutes of Health

Grant: 3P30CA016086-42S2

Cancer Center Support Grant

American Epilepsy Society

Finding A Cure for Epilepsy and Seizures

Miami Clinical and Translational Science Institute, University of Miami

National Center for Advancing Translational Sciences

NIH

FWCI

0.80

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.omtn.2024.102441

publisherhttps://doi.org/10.1016/j.omtn.2024.102441

publisherhttps://api.elsevier.com/content/article/PII:S2162253124003287?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2162253124003287?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39877004

Fields of Study

CRISPR and Genetic EngineeringGenetics and Neurodevelopmental DisordersRNA Interference and Gene Delivery

Keywords

Induced pluripotent stem cellBiologyMutantInclusion bodiesHEK 293 cellsProtein aggregationGenome editingCell biologyProgrammed cell deathNeuroscienceGeneCRISPRGeneticsEmbryonic stem cellApoptosisRecombinant DNAProtein Conformational DiseaseCrispr-cas9Ipsc-derived NeuronsAdenine Base EditingEngineered Virus-Like ParticlesMt: Rna/Dna EditingOriginal ArticleTherapeutics. PharmacologyRM1-950

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Zero hunger