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Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse model

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102466Source: DataRank Database

Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse model is a research paper published in Molecular Therapy — Nucleic Acids (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (6 grants)OA: goldTopics (10)IDs (PubMed, PMC)Annotations (2)

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Authors (14)

Dawn Madison Frederick,Nutan Sharma ORCID,Edwina Abou Haidar ORCID,Tianhe Xiao,Justin Seungkyu Han

Live enrichment

PubMed:40114706 PMC:PMC11925580

National Institutes of Health

Grant: DOD HT9425-24-1-0119

NIH NCI

Grant: K22 CA2802019-01

NCI NIH HHS

Grant: K22 CA282019

Massachusetts General Hospital

US Department of Defense

Friedreich's Ataxia Research Alliance

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.omtn.2025.102466

publisherhttps://api.elsevier.com/content/article/PII:S2162253125000204?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2162253125000204?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11925580/pdf/main.pdf

repositoryhttps://doaj.org/article/fca4650316e64ce28398ce2b08302607

Keywords

Adeno-associated virus vectorExtracellular VesiclesTor1aTheranosticDyt1 DystoniaExrnaCrispr/cas Gene EditingMt: Rna/Dna EditingSacas9-kkhDgag

Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse model

FAIR Checklist

Authors (14)

Funding (6 grants)

Open Access

Topics

Annotations (Europe PMC)