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Installation of dominant-negative mutations in FAS and TGFβR2 via base editing in primary T cells

Molecular Therapy Oncology(2025)10.1016/j.omton.2025.201063Source: DataRank Database

Installation of dominant-negative mutations in FAS and TGFβR2 via base editing in primary T cells is a research paper published in Molecular Therapy Oncology (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (19 grants)Impact (FWCI 0.00)OA: goldTopics (18)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Mitchell G. Kluesner ORCID,Nicholas J. Slipek ORCID,Joseph G. Skeate ORCID,Ethan M. Niemeyer,Beau R. Webber ORCID

Live enrichment

PubMed:41141367 PMC:PMC12547302 OpenAlex:https://openalex.org/W4414475685

Randy Shaver Cancer Research and Community Fund

Grant: R21CA237789

Randy Shaver Cancer Research and Community Fund

Grant: R21AI163731

National Institutes of Health

Grant: U24OD026641

National Institutes of Health

Grant: R01AI161017

National Institutes of Health

Grant: U54CA232561

National Institutes of Health

Grant: R01AI146009

National Institutes of Health

Grant: P01CA254849

National Institutes of Health

Grant: U54CA268069

National Institutes of Health

Grant: P50CA136393

National Institutes of Health

Grant: P30CA077598

National Institutes of Health

Grant: HT94252410231

NCI NIH HHS

Grant: F30 CA305905

NIA NIH HHS

Grant: R61 AG090358

NCI NIH HHS

Grant: R37 CA276345

NHLBI NIH HHS

Grant: T32 HL007062

Children's Cancer Research Fund

Alex's Lemonade Stand Foundation for Childhood Cancer

MIB Agents

Fanconi Cancer Foundation

FWCI

0.00

Citation Percentile

0.2%

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.omton.2025.201063

publisherhttps://doi.org/10.1016/j.omton.2025.201063

publisherhttps://api.elsevier.com/content/article/PII:S2950329925001328?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2950329925001328?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41141367

Fields of Study

Immune Cell Function and InteractionPeptidase Inhibition and AnalysisCell Adhesion Molecules Research

Keywords

Chimeric antigen receptorMultiplexT cellTumor microenvironmentAntigenAdoptive cell transferT-cell receptorReceptorPhenotypeT cellsCancer ImmunotherapyCar-tBase EditorsDominant-negative MutationsMt: Regular Issue

Installation of dominant-negative mutations in FAS and TGFβR2 via base editing in primary T cells

FAIR Checklist

Authors (7)

Funding (19 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)