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Distinctive biochemical properties of the μ-opioid receptor-corticotropin- releasing factor CRF1 receptor heterotetramer

Pharmacological Research(2025)10.1016/j.phrs.2025.107904Source: DataRank Database

Distinctive biochemical properties of the μ-opioid receptor-corticotropin- releasing factor CRF1 receptor heterotetramer is a research paper published in Pharmacological Research (2025). On theSindex it has a DataRank of 0.254. It has been cited 4 times, with 1 citing works in its 1-hop citation network.

N/A

0.254DataRank · unranked

Scored on demand from live citation data

Open Access4 citations · 1 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 1.54)OA: goldTopics (44)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 95%Citation Network 5%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

0.0125

From 1 citing papers with measurable signal

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Top 1 citer driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 1 citer.

Mechanism of μ-opioid receptor inhibition by orphan GPR88
Pharmacological Research20262 citations75 referencesContributes 0.015

Authors (12)

Estefanía Moreno ORCID,Marc Ciruela-Jardí ORCID,Nil Casajuana-Martín ORCID,Anne K. Yauch ORCID,Ning-Sheng Cai ORCID

Live enrichment

PubMed:40784438 OpenAlex:https://openalex.org/W4413102276

National Institute on Drug Abuse

Grant: PID2020\u2013113938RB-I00

National Institute on Drug Abuse

Grant: PID2022\u2013140912OB-I00

National Institute on Drug Abuse

Grant: PID2023\u2013146914OB-I00

National Institute on Drug Abuse

Grant: MCIN/AEI/10.13039/501100011033

Barcelona Supercomputing Center

Grant: RES-BCV-2024\u20132\u20130002

Department of Health

Grant: 2021-SGR-00230

Intramural Research Program, National Institute on Drug Abuse

Grant: ZIA DA000493

Generalitat de Catalunya

Federación Española de Enfermedades Raras

Ministerio de Ciencia e Innovación

FWCI

1.54

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.phrs.2025.107904

publisherhttps://doi.org/10.1016/j.phrs.2025.107904

publisherhttps://api.elsevier.com/content/article/PII:S1043661825003299?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1043661825003299?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40784438

Fields of Study

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology ResearchStress Responses and CortisolReceptors, Corticotropin-Releasing HormoneCRF Receptor, Type 1Receptors, Opioid, muAnimalsHumansHEK293 CellsProtein MultimerizationAnalgesics, OpioidAdenylyl Cyclases

MeSH Terms

CRF Receptor, Type 1Adenylyl CyclasesAnalgesics, OpioidAnimalsHumansReceptors, Opioid, muReceptors, Corticotropin-Releasing HormoneProtein MultimerizationHEK293 Cells

Keywords

HeterotetramerChemistryAdenylyl cyclaseAllosteric regulationDADLENociceptin receptorPharmacologyMetabotropic receptorReceptorCell biologyOpioid receptorBiochemistryOpioidProtein subunitAgonistBiologyOpioid peptidePhospholipase CCalcium signalingHeteromersCentral AmygdalaΜ-opioid ReceptorCrf(1) Receptor