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HYPOTHESIS: Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimer's disease in humans

Prostaglandins Leukotrienes and Essential Fatty Acids(2025)10.1016/j.plefa.2025.102681Source: DataRank Database

HYPOTHESIS: Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimer's disease in humans is a research paper published in Prostaglandins Leukotrienes and Essential Fatty Acids (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: hybridTopics (26)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Roy G. Cutler ORCID,Xiufeng Li ORCID,Gregory S. Keyes ORCID,Christopher E. Ramsden ORCID

Live enrichment

PubMed:40209641 OpenAlex:https://openalex.org/W4409189372

National Institute on Aging

Grant: 1ZIAAG000453

Intramural NIH HHS

Grant: Z99 AG999999

Intramural NIH HHS

Grant: ZIA AG000453

Intramural NIH HHS

Grant: ZIA AG000456

FWCI

0.00

Citation Percentile

0.1%

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.plefa.2025.102681

publisherhttps://doi.org/10.1016/j.plefa.2025.102681

publisherhttps://api.elsevier.com/content/article/PII:S0952327825000183?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0952327825000183?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40209641

Fields of Study

Alzheimer's disease research and treatmentsComputational Drug Discovery MethodsBiochemical Acid Research Studies

MeSH Terms

Alzheimer DiseaseBrainDisulfidesHumansAmyloid beta-PeptidesApolipoprotein E3Apolipoprotein E4

Keywords

DiseaseDisulfide bondAlzheimer's diseaseLink (geometry)MedicineChemistryBiochemistryInternal medicineComputer scienceLipid PeroxidationApolipoprotein EDocosahexaenoic acidDisulfideAlzheimerApolipoprotein JPolyunsaturated