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Chronic sucralose consumption inhibits farnesoid X receptor signaling and perturbs lipid and cholesterol homeostasis in the mouse livers, potentially by altering gut microbiota functions

The Science of The Total Environment(2024)10.1016/j.scitotenv.2023.169603Source: DataRank Database

Chronic sucralose consumption inhibits farnesoid X receptor signaling and perturbs lipid and cholesterol homeostasis in the mouse livers, potentially by altering gut microbiota functions is a research paper published in The Science of The Total Environment (2024). On theSindex it has a DataRank of 0. It has been cited 15 times.

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15 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 2.38)OA: closedTopics (47)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Yifei Yang ORCID,Xiaoming Bian,Bei Gao ORCID,Pengcheng Tu ORCID,Hongyu Ru ORCID

Live enrichment

PubMed:38272087 OpenAlex:https://openalex.org/W4391132144

Center for Environmental Health and Susceptibility, University of North Carolina at Chapel Hill

Grant: P30ES010126

Center for Environmental Health and Susceptibility, University of North Carolina at Chapel Hill

Grant: P42ES031007

National Institutes of Health

Grant: R01ES024950

National Institutes of Health

Grant: R03ES032067

FWCI

2.38

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

closedLicense: https://doi.org/10.15223/policy-004

publisherhttps://api.elsevier.com/content/article/PII:S0048969723082335?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0048969723082335?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.scitotenv.2023.169603

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38272087

Fields of Study

Gut microbiota and healthBiochemical Analysis and Sensing TechniquesDrug Transport and Resistance MechanismsMiceAnimalsGastrointestinal MicrobiomeReceptors, Cytoplasmic and NuclearLiverHomeostasisCholesterolBile Acids and SaltsLipidsMice, Inbred C57BLSucrose

MeSH Terms

Gastrointestinal MicrobiomeAnimalsBile Acids and SaltsCholesterolHomeostasisLipidsLiverMice, Inbred C57BLSucroseReceptors, Cytoplasmic and NuclearMice

Keywords

SucraloseFarnesoid X receptorBile acidGut floraEndocrinologyInternal medicineCholesterolG protein-coupled bile acid receptorBiologyMicrobiomeCholesterol 7 alpha-hydroxylaseChemistryBiochemistryNuclear receptorTranscription factorGeneMedicineFood scienceBile acidsFXRGut microbiotaNonalcoholic fatty liver disease

Sustainable Development Goals

SDG 0: Zero hunger

Chronic sucralose consumption inhibits farnesoid X receptor signaling and perturbs lipid and cholesterol homeostasis in the mouse livers, potentially by altering gut microbiota functions

FAIR Checklist

Authors (7)

Funding (4 grants)

Impact

Open Access

Topics