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A phenotypic screen for compounds that reverse cAMP-mediated suppression of T cell functions

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.03.008Source: DataRank Database

A phenotypic screen for compounds that reverse cAMP-mediated suppression of T cell functions is a research paper published in SLAS DISCOVERY (2022). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.08)OA: goldTopics (31)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Meghan Wyatt ORCID,Haim Bar ORCID,Mark K. Haynes,Bruce S. Edwards,Larry A. Sklar ORCID

Live enrichment

PubMed:35385793 OpenAlex:https://openalex.org/W4224008668

National Institutes of Health

Grant: AI121069

National Institutes of Health

Grant: P30CA118100

National Institutes of Health

Grant: UL1TR001449

NIAID NIH HHS

Grant: R01 AI121069

University of Connecticut

FWCI

0.08

Citation Percentile

0.3%

Citation Trend

2024

goldLicense: cc-by-nc-nd

journalhttp://slas-discovery.org/article/S2472555222126596/pdf

publisherhttp://slas-discovery.org/article/S2472555222126596/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2472555222126596?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2472555222126596?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.slasd.2022.03.008

Fields of Study

Immune Cell Function and InteractionCAR-T cell therapy researchImmunotherapy and Immune Responses

MeSH Terms

Cyclic AMPExocytosisFlow CytometryHumansT-Lymphocytes, CytotoxicSignal Transduction

Keywords

Lytic cycleExocytosisFlow cytometryImmunological synapseBiologyJurkat cellsCell biologyCytotoxic T cellCD3Molecular biologyT cellImmune systemSecretionT-cell receptorBiochemistryImmunologyIn vitroCD8CancerImmunityCell signalingTumor Microenvironment

Sustainable Development Goals

SDG 0: Good health and well-being