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Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids

Cell stem cell(2021)10.1016/j.stem.2021.08.015Source: DataRank Database

Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids is a research paper published in Cell stem cell (2021). On theSindex it has a DataRank of 0. It has been cited 229 times.

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Open Access229 citations

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geo gen cellosaurus hpa

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Enrichment:Funding (15 grants)Impact (FWCI 12.98)OA: greenTopics (73)Linked Datasets (22)DataCite Reuse (22)IDs (PubMed, PMC, OpenAlex)Annotations (4)

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Accessible (1/2)

Open Access

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Authors (19)

Sarah S. Soliman ORCID,Chang N. Kim ORCID,Matthew G. Keefe ORCID,Kelsey M. Hennick ORCID,Samhita Jain ORCID

Live enrichment

PubMed:34536354 PMC:PMC8642295 OpenAlex:https://openalex.org/W3200461021

Simons Foundation

Grant: SFARI 491371

National Institutes of Health

Grant: P01 NS083513

National Institutes of Health

Grant: R01 NS118442

National Institutes of Health

Grant: R01 NS108446

NHGRI NIH HHS

Grant: U41 HG002371

NICHD NIH HHS

Grant: T32 HD007470

NIMH NIH HHS

Grant: U01 MH116438

NIGMS NIH HHS

Grant: T32 GM007810

NIMH NIH HHS

Grant: F32 MH118785

NHGRI NIH HHS

Grant: U24 HG002371

NIMH NIH HHS

Grant: RF1 MH121268

NIMH NIH HHS

Grant: RF1 MH132662

NINDS NIH HHS

Grant: RF1 NS118442

National Institutes of Health

Grant: 5F32MH118785-03

Elucidating molecular mechanisms regulatingspatiotemporal heterogeneity of microglia in the developing human brain

SFARI

FWCI

12.98

Citation Percentile

1.0%

Citation Trend

2012

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2021

2022

2023

2024

2025

2026

greenLicense: Elsevier Non-Commercial

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8642295

publisherhttps://api.elsevier.com/content/article/PII:S1934590921003763?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1934590921003763?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.stem.2021.08.015

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancerBarrier Structure and Function Studies03 medical and health sciences0303 health sciencesBrainCell DifferentiationHumansInduced Pluripotent Stem CellsMicrogliaModels, TheoreticalNeural Stem CellsOrganoids

MeSH Terms

BrainCell DifferentiationHumansModels, TheoreticalOrganoidsMicrogliaInduced Pluripotent Stem CellsNeural Stem Cells

Keywords

MicrogliaBiologyOrganoidInduced pluripotent stem cellStem cellNeuroscienceNeural stem cellCell typeCell biologyPhenotypeCellular differentiationCellEmbryonic stem cellGeneImmunologyGeneticsInflammationOrganoidsInterferon ResponseIpscNeuro-immuneHuman MicrogliaDouble-stranded Dna BreaksMicroglia CultureInduced MicrogliaOrganoid Activity570Biomedical and clinical sciences1.1 Normal biological development and functioningMedical BiotechnologyInduced Pluripotent Stem Cells610Regenerative MedicineMedical and Health SciencesTheoreticalNeural Stem CellsModels2.1 Biological and endogenous factorsHumansStem Cell Research - Embryonic - HumanStem Cell Research - Induced Pluripotent Stem CellStem Cell Research - Induced Pluripotent Stem Cell - HumanNeurosciencesBrainCell DifferentiationBiological SciencesModels, TheoreticalStem Cell ResearchBrain DisordersStem Cell Research - Nonembryonic - Non-HumanBiotechnologyDevelopmental Biology

Additional file 1 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 1 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 2 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 2 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 3 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 3 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 4 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 4 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 5 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 5 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 6 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 6 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 7 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 7 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 14 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 14 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 15 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 15 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 16 of Human cortical spheroids with a high diversity of innately developing brain cell types

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Additional file 16 of Human cortical spheroids with a high diversity of innately developing brain cell types

10.6084/m9.figshare.22617517figshare

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Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids

FAIR Checklist

Authors (19)

Funding (15 grants)

Impact

Open Access

Topics

Linked Datasets (22)

Annotations (Europe PMC)

Related Papers (10)