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A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection

Cell stem cell(2024)10.1016/j.stem.2024.03.002Source: DataRank Database

A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection is a research paper published in Cell stem cell (2024). On theSindex it has a DataRank of 0. It has been cited 15 times.

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Open Access15 citations

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Enrichment:Funding (10 grants)OA: bronzeTopics (17)IDs (PubMed, PMC)Annotations (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

William N. Feist ORCID,Elena J. Sasu,Sofia E. Luna ORCID,Kaya Ben-Efraim,Rasmus O. Bak ORCID

Live enrichment

PubMed:38579682 PMC:PMC11212398

National Institutes of Health

Grant: 1K99HL172253-01

National Institutes of Health

Grant: DFF-1331-00735B

National Institutes of Health

Grant: DFF-1333-00106B

National Institutes of Health

Grant: 1F32HL154667-01

NIGMS NIH HHS

Grant: T32 GM119995

NHLBI NIH HHS

Grant: K99 HL172253

NHLBI NIH HHS

Grant: F32 HL154667

NIAID NIH HHS

Grant: R01 AI120766

Danmarks Frie Forskningsfond

Blavatnik Family Foundation

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttp://www.cell.com/article/S1934590924000833/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1934590924000833?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1934590924000833?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11212398/pdf/nihms-1978016.pdf

https://pure.au.dk/portal/en/publications/ffac83d4-17ac-427d-837e-2b6828e0943a

MeSH Terms

Hematopoietic Stem CellsHumansHIV-1HIV InfectionsReceptors, CCR5Receptors, CXCR4Gene Editing

Keywords

HIVCell therapyGene EditingHematopoietic Stem Cell TransplantHomology-directed RepairFunctional CureCrispr-cas9Hiv RestrictionAutologous HsctCcr5 Knockout

A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection

FAIR Checklist

Authors (8)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)