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BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate

Cell stem cell(2024)10.1016/j.stem.2024.10.014Source: DataRank Database

BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate is a research paper published in Cell stem cell (2024). On theSindex it has a DataRank of 0. It has been cited 16 times.

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16 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)Impact (FWCI 3.92)OA: closedTopics (54)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (41)

Jing Zeng ORCID,Rahul Palchaudhuri ORCID,Chuanfeng Wu ORCID,Diana M. Abraham ORCID,Taha Bartu Hayal ORCID

Live enrichment

PubMed:39642886 OpenAlex:https://openalex.org/W4405036934

National Heart Lung and Blood Institute

Grant: 1OT2HL154984-01

National Institutes of Health

Grant: P01HL053749

National Institutes of Health

Grant: 1R01HL150669-04

Foundation for the National Institutes of Health

Doris Duke Charitable Foundation

Division of Intramural Research

Harvard Stem Cell Institute

FWCI

3.92

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

closedLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttps://api.elsevier.com/content/article/PII:S193459092400376X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S193459092400376X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.stem.2024.10.014

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39642886

Fields of Study

Erythrocyte Function and PathophysiologyBlood groups and transfusionHemoglobinopathies and Related DisordersAnimalsMacaca mulattaHematopoietic Stem CellsFetal HemoglobinLeukocyte Common AntigensImmunoconjugatesHematopoietic Stem Cell TransplantationGene EditingEnhancer Elements, GeneticTransplantation ConditioningRepressor ProteinsBusulfanHumans

MeSH Terms

Gene EditingAnimalsBusulfanEnhancer Elements, GeneticFetal HemoglobinHematopoietic Stem CellsHumansMacaca mulattaRepressor ProteinsLeukocyte Common AntigensHematopoietic Stem Cell TransplantationImmunoconjugatesTransplantation Conditioning

Keywords

BiologyEnhancerConjugateAntibody-drug conjugateAntibodyDrugCell biologyImmunologyPharmacologyCancer researchMolecular biologyMonoclonal antibodyGeneticsTranscription factorGeneHydroxyureaBusulfanFetal HemoglobinSickle Cell DiseaseCrispr-cas9Γ-globinΒ-globin DisordersHsc TransplantationTherapeutic Gene EditingAntibody Conditioning

Sustainable Development Goals

SDG 0: Zero hunger