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Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis

Stem Cell Reports(2020)10.1016/j.stemcr.2019.12.009Source: DataRank Database

Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis is a research paper published in Stem Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.81)OA: goldTopics (67)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

G. Devon Trahan ORCID,Elizabeth D. Howell ORCID,Nancy A. Speck ORCID,Kenneth L. Jones ORCID,Austin E. Gillen ORCID

Live enrichment

PubMed:31951812 PMC:PMC7013201 OpenAlex:https://openalex.org/W2998947592

NIDDK NIH HHS

Grant: R01 DK120369

NHLBI NIH HHS

Grant: R01 HL091724

NIH HHS

Grant: R21 OD019716

National Institutes of Health

Grant: 3P30CA046934-20S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5R21OD019716-03

Modeling hematologic malignancy and self-renewal with gain-of-function MLL1

National Institutes of Health

FWCI

0.81

Citation Percentile

0.7%

Citation Trend

2020

2021

2022

2023

2025

goldLicense: cc-by-nc-nd

journalhttps://www.cell.com/stem-cell-reports/pdf/S2213-6711(19)30448-5.pdf

publisherhttps://www.cell.com/stem-cell-reports/pdf/S2213-6711(19)30448-5.pdf

publisherhttps://api.elsevier.com/content/article/PII:S2213671119304485?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2213671119304485?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.stemcr.2019.12.009

Fields of Study

Zebrafish Biomedical Research ApplicationsAcute Myeloid Leukemia ResearchPluripotent Stem Cells Research0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Mouse Embryonic Stem CellsAnimalsCell AdhesionCell DifferentiationColony-Forming Units AssayHematopoiesisHematopoietic Stem CellsHumansMesodermHistone-Lysine N-MethyltransferaseSignal TransductionBiomarkersIntegrinsrho GTP-Binding Proteinsrac GTP-Binding ProteinsMiceMyeloid-Lymphoid Leukemia ProteinEmbryoid Bodies

Keywords

BiologyHaematopoiesisStem cellEmbryonic stem cellCell biologyPopulationHematopoietic stem cellEmbryoid bodyIntegrinHemangioblastGeneticsAdult stem cellCellGeneEMPHemogenic EndotheliumEmbryonic HematopoiesisKmt2aSingle-cell Rna SequencingProgenitor Heterogeneityrho GTP-Binding ProteinsMedicine (General)IntegrinsQH301-705.5ArticleColony-Forming Units AssayMesodermMiceR5-920Cell AdhesionAnimalsHumansBiology (General)Embryoid BodiesCell DifferentiationMouse Embryonic Stem CellsHistone-Lysine N-MethyltransferaseHematopoietic Stem CellsHematopoiesisrac GTP-Binding ProteinsBiomarkersMyeloid-Lymphoid Leukemia ProteinSignal Transduction

Sustainable Development Goals

SDG 0: Partnerships for the goals