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MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

Structure(2020)10.1016/j.str.2020.01.003Source: DataRank Database

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling is a research paper published in Structure (2020). On theSindex it has a DataRank of 0. It has been cited 81 times.

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Enrichment:Funding (20 grants)Impact (FWCI 3.08)OA: hybridTopics (45)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (8)

Daniel Bollschweiler ORCID,Bing Li ORCID,Pawel A. Penczek ORCID,Lee Hopkins ORCID,Clare Bryant ORCID

Live enrichment

PubMed:31995744 PMC:PMC7054835 OpenAlex:https://openalex.org/W3003838913

National Institutes of Health

Grant: R01 GM60635

National Institutes of Health

Grant: P01 GM 121203

Royal Society

Grant: RP150066

Royal Society

Grant: 202905/Z/16/Z

Royal Society

Grant: 108045/Z/15/Z

Royal Society

Grant: 206171/Z/17/Z

Wellcome Trust

Grant: WT100321/z/12/Z

University of Massachusetts Medical School

Grant: GFPMyD88

University of Massachusetts Medical School

Grant: MyD88\u2212/\u2212

NIGMS NIH HHS

Grant: R01 GM060635

Wellcome Trust

Grant: 100321/Z/12/Z

Biotechnology and Biological Sciences Research Council

Grant: BB/H003916/1

Wellcome Trust

Grant: 108045

Inflammasome formation in infectious and inflammatory diseases.

Wellcome Trust

Grant: 202905

An electron cryo-microscopy resource for macromolecular structure determination in the University of Cambridge

Wellcome Trust

Grant: 100321

Molecular mechanism of innate signalling in the immune and nervous system.

National Institutes of Health

Grant: 1P01GM121203-01A1

An automated pipeline for macromolecular structure discovery in cellular electron cryo-tomography

Wellcome Trust

Grant: 206171

An advanced cryoEM instrument for the University of Cambridge

National Institutes of Health

Grant: 5R01GM060635-16

High Resolution in Single Particle Reconstruction

Wellcome Trust

University of Cambridge

FWCI

3.08

Citation Percentile

0.9%

Influential Citations

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttp://www.cell.com/article/S0969212620300034/pdf

HYBRIDhttps://www.cell.com/article/S0969212620300034/pdf

publisherhttp://www.cell.com/article/S0969212620300034/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969212620300034?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212620300034?httpAccept=text/plain

Fields of Study

Immune Response and InflammationImmune cells in cancerNeutrophil, Myeloperoxidase and Oxidative MechanismsMedicineChemistryBiology0301 basic medicine03 medical and health sciences

MeSH Terms

Protein DomainsHumansModels, MolecularSignal TransductionProtein Structure, SecondaryCrystallography, X-RayCryoelectron MicroscopyInterleukin-1 Receptor-Associated KinasesMyeloid Differentiation Factor 88Protein Multimerization

Keywords

Cell biologyInnate immune systemReceptorBiologySignal transductionToll-like receptorSignal transducing adaptor proteinProtein filamentBiophysicsBiochemistryMyD88Tlr SignalingCryo-emTirfmIrakLight-sheet MicroscopyMyddosomeModels, MolecularCryoelectron MicroscopyCrystallography, X-RayArticleProtein Structure, SecondaryInterleukin-1 Receptor-Associated KinasesProtein DomainsMyeloid Differentiation Factor 88HumansProtein Multimerization

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 2 of Mechanism of MyD88S mediated signal termination

10.6084/m9.figshare.18849165.v1figshare

Additional file 2 of Mechanism of MyD88S mediated signal termination

10.6084/m9.figshare.18849165figshare

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

FAIR Checklist

Authors (8)

Funding (20 grants)

Impact

Open Access

Topics

Linked Datasets (2)

Annotations (Europe PMC)