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Structure of an inactive conformation of GTP-bound RhoA GTPase

Structure(2021)10.1016/j.str.2020.12.015Source: DataRank Database

Structure of an inactive conformation of GTP-bound RhoA GTPase is a research paper published in Structure (2021). On theSindex it has a DataRank of 0. It has been cited 28 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access28 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 1.41)OA: bronzeTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Shaoyong Lu ORCID,Jian Zhang ORCID,Yi Zheng ORCID,Yuan Lin ORCID

Live enrichment

PubMed:33497604 PMC:PMC8178163 OpenAlex:https://openalex.org/W3125994377

NHLBI NIH HHS

Grant: R01 HL147536

National Institutes of Health

Grant: 5R01HL147536-02

Small molecules targeting RhoA for platelet cold storage in cancer care

CancerFree KIDS

National Institutes of Health

FWCI

1.41

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S0969212620304822/pdf

publisherhttp://www.cell.com/article/S0969212620304822/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969212620304822?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212620304822?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.str.2020.12.015

Fields of Study

Protein Kinase Regulation and GTPase SignalingCellular transport and secretionEnzyme Structure and Function0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Guanosine DiphosphateGuanosine TriphosphateHumansModels, MolecularMutationProtein ConformationCrystallography, X-RayrhoA GTP-Binding ProteinMolecular Dynamics Simulation

Keywords

RHOAGTP'GTPaseSmall GTPaseChemistryMutantMolecular switchBiophysicsCrystallographyBiologyMoleculeBiochemistrySignal transductionEnzymeCrystal structureMolecular dynamicsConformational DynamicsConstitutively Active MutantModels, MolecularProtein ConformationMutationHumansGuanosine TriphosphateMolecular Dynamics SimulationCrystallography, X-RayrhoA GTP-Binding ProteinGuanosine Diphosphate

Sustainable Development Goals

SDG 0: Decent work and economic growth

Structure of an inactive conformation of GTP-bound RhoA GTPase

FAIR Checklist

Authors (4)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)