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Two steps, one ligand: How PPARγ binds small-molecule agonists

Structure(2021)10.1016/j.str.2021.08.005Source: DataRank Database

Two steps, one ligand: How PPARγ binds small-molecule agonists is a research paper published in Structure (2021). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.07)OA: bronzeTopics (31)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Kevin H. Gardner ORCID,James J. Siclari ORCID

Live enrichment

PubMed:34478635 PMC:PMC8819882 OpenAlex:https://openalex.org/W3196830772

National Science Foundation

Grant: MCB 1818148

National Institutes of Health

Grant: R01 GM106239

National Science Foundation

Grant: 1818148

Protein Structural Defects: Sites for Small Molecule Binding and Regulation

National Institutes of Health

Grant: 3R01GM106239-12S1

Summer Undergraduate Research Support - Ms. Anastasiia Fisiuk

NSF

FWCI

0.07

Citation Percentile

0.4%

Citation Trend

2022

2025

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S0969212621003002/pdf

publisherhttp://www.cell.com/article/S0969212621003002/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969212621003002?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212621003002?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.str.2021.08.005

Fields of Study

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and MetabolismAdenosine and Purinergic Signaling0301 basic medicine0303 health sciences03 medical and health sciencesLigandsPPAR gammaThiazolidinediones

MeSH Terms

LigandsThiazolidinedionesPPAR gamma

Keywords

Mechanism (biology)Nuclear receptorChemistryReceptorSmall moleculeLigand (biochemistry)BiophysicsDrug discoveryComputational biologyBinding siteStereochemistryBiochemistryBiologyTranscription factorGenePhysicsPPAR gammaThiazolidinedionesLigands

Sustainable Development Goals

SDG 0: Good health and well-being