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Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

Structure(2023)10.1016/j.str.2023.01.009Source: DataRank Database

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps is a research paper published in Structure (2023). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.68)OA: bronzeTopics (67)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (26)

Gregory E. Merz ORCID,Axel F. Brilot ORCID,Un Seng Chio ORCID,Alexandrea N. Rizo ORCID,Thomas H. Pospiech ORCID

Live enrichment

PubMed:36805129 PMC:PMC9936628 OpenAlex:https://openalex.org/W4321208422

NIGMS NIH HHS

Grant: R35 GM122451

NIGMS NIH HHS

Grant: T32 GM145460

NIGMS NIH HHS

Grant: R00 GM135529

NIGMS NIH HHS

Grant: K99 GM135529

National Institutes of Health

Grant: 5K99GM135529-02

Mapping and rewiring protein allostery

National Institutes of Health

Grant: 5R35GM122451-05

Discovering how oncogenes remodel the surfaceome of cells

FWCI

0.68

Citation Percentile

0.6%

Citation Trend

2023

2024

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S0969212623000308/pdf

publisherhttp://www.cell.com/article/S0969212623000308/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969212623000308?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212623000308?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.str.2023.01.009

Fields of Study

SARS-CoV-2 and COVID-19 ResearchVirus-based gene therapy researchMonoclonal and Polyclonal Antibodies Research0301 basic medicine03 medical and health sciences0303 health sciencesHumansAngiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Antibodies, MonoclonalProtein BindingAntibodies, NeutralizingSARS-CoV-2 variants

MeSH Terms

Angiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Antibodies, MonoclonalHumansProtein BindingAntibodies, Neutralizing

Keywords

EctodomainReceptorChemistryBiophysicsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cell biologyCoronavirus disease 2019 (COVID-19)BiologyComputational biologyBiochemistryMedicinespikeProtein TherapeuticsCryo-emRosettaPseudovirus NeutralizationSars-cov-2 Omicron VariantAce2 Receptor TrapsQCRG Structural Biology ConsortiumBioengineeringAntibodiesArticleVaccine RelatedBiodefenseInformation and Computing SciencesMonoclonal2.1 Biological and endogenous factorsHumansAetiologyNeutralizingLungSARS-CoV-2PreventionCOVID-19Antibodies, MonoclonalPneumoniaBiological SciencesAntibodies, NeutralizingEmerging Infectious DiseasesInfectious DiseasesGood Health and Well BeingChemical SciencesPneumonia & InfluenzaAngiotensin-Converting Enzyme 2InfectionProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Affordable and clean energy