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Structure-function analyses of human TRPV6 ancestral and derived haplotypes

Structure(2024)10.1016/j.str.2024.10.018Source: DataRank Database

Structure-function analyses of human TRPV6 ancestral and derived haplotypes is a research paper published in Structure (2024). On theSindex it has a DataRank of 0.329. It has been cited 7 times, with 5 citing works in its 1-hop citation network.

N/A

0.329DataRank · unranked

Scored on demand from live citation data

Open Access7 citations · 5 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 1.83)OA: greenTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 95%Citation Network 5%

Base Score Contribution

0.312

From this paper's citation signal

Citation Network Contribution

0.0169

From 2 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 5 citers.

TRPV6 channel function is involved in endometrial epithelial cell Ca2+ signaling and female mouse fecundity
Cellular and Molecular Life Sciences20252 citations73 referencesContributes 0.015
Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin
The Journal of Physiology20261 citations142 referencesContributes 0.005
TRP channels as drug targets: Structural insights and therapeutic relevance
Elsevier eBooks20260 citations1,348 referencesContributes 0.000
Ligand-Mediated Conformational Plasticity of the Pore Domain of TRPV6 Ion Channel
Russian Journal of Bioorganic Chemistry20260 citations38 referencesContributes 0.000
Discovery of the small molecular inhibitors against TRPV6 as potential anti-cancer agents by structural based virtual screening
Frontiers in Chemistry20260 citations44 referencesContributes 0.000

Authors (10)

Alexey Shalygin ORCID,Yu. A. Trofimov ORCID,Irina I. Veretenenko ORCID,Kirill D. Nadezhdin ORCID,Nikolay A. Krylov ORCID

Live enrichment

PubMed:39500315 PMC:PMC11698656 OpenAlex:https://openalex.org/W4404023901

Simons Foundation

Grant: SF349247

Deutsche Forschungsgemeinschaft

Grant: R37 NS083660

Deutsche Forschungsgemeinschaft

Grant: R01 AR078814

Deutsche Forschungsgemeinschaft

Grant: TRR 152

Deutsche Forschungsgemeinschaft

Grant: 464295817

Deutsche Forschungsgemeinschaft

Grant: R01 NS107253

Deutsche Forschungsgemeinschaft

Grant: R01 CA206573

Deutsche Forschungsgemeinschaft

Grant: GRK 2338 RTG (P10

RSF Social Finance

Grant: 23-14-00313

National Institutes of Health

Grant: U24 GM129539

NINDS NIH HHS

Grant: R01 NS083660

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Foundation for the National Institutes of Health

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Neurological Disorders and Stroke

Ludwig-Maximilians-Universität München

FWCI

1.83

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: Elsevier Non-Commercial

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11698656/pdf/nihms-2029900.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0969212624004532?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212624004532?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11698656/

Fields of Study

Ion Channels and ReceptorsRNA regulation and diseaseCalcium signaling and nucleotide metabolism0301 basic medicine03 medical and health sciences

MeSH Terms

Binding SitesCalciumCalmodulinHaplotypesHumansModels, MolecularProtein BindingStructure-Activity RelationshipCalcium ChannelsCryoelectron MicroscopyPolymorphism, Single NucleotideTRPV Cation ChannelsHEK293 Cells

Keywords

HaplotypeFunction (biology)GeneticsBiologyComputational biologyEvolutionary biologyGeneGenotypeCancerTrp ChannelsDerivedTrpv6Cryo-emAncestralOncochannelDynamic Molecular Portraits Of Trpv6 Pore DomainModels, MolecularBinding SitesCryoelectron MicroscopyTRPV Cation ChannelsPolymorphism, Single NucleotideArticleStructure-Activity RelationshipHEK293 CellsHaplotypesCalmodulinHumansCalciumCalcium ChannelsProtein Binding

Sustainable Development Goals

SDG 0: Zero hunger

Structure-function analyses of human TRPV6 ancestral and derived haplotypes

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (10)

Funding (16 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)