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Initial leads to combat streptogramin resistance generated from X-ray fragment screening against VatD

Structure(2025)10.1016/j.str.2025.08.017Source: DataRank Database

Initial leads to combat streptogramin resistance generated from X-ray fragment screening against VatD is a research paper published in Structure (2025). On theSindex it has a DataRank of 0.

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0DataRank · unranked

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Open Access0 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: greenTopics (33)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Sonya Lee,Christian M. MacDonald,Ian B. Seiple ORCID,James S. Fraser ORCID,Pooja Asthana ORCID

Live enrichment

PubMed:40945513 OpenAlex:https://openalex.org/W4414163838

NIH

Grant: GM145238

National Institute of General Medical Sciences

Grant: P30GM133894

Basic Energy Sciences

Grant: DE-AC02-76SF00515

Office of Science

Grant: P30GM124169

Office of Science

Grant: DE-AC02-05CH11231

NIGMS NIH HHS

Grant: R35 GM145238

FWCI

0.00

Citation Percentile

0.2%

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12435910/

publisherhttps://api.elsevier.com/content/article/PII:S0969212625003211?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212625003211?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.str.2025.08.017

Fields of Study

Antibiotics Pharmacokinetics and EfficacyAntimicrobial Resistance in StaphylococcusAntibiotic Resistance in BacteriaCrystallography, X-RayAnti-Bacterial AgentsBinding SitesBacterial ProteinsAcetyltransferasesStreptograminsDrug Resistance, BacterialProtein BindingModels, Molecular

MeSH Terms

AcetyltransferasesAnti-Bacterial AgentsBacterial ProteinsBinding SitesModels, MolecularProtein BindingCrystallography, X-RayDrug Resistance, BacterialStreptogramins

Keywords

VirginiamycinAntibioticsAcetylationLincosamidesAntibiotic resistanceDrug discoveryDrug resistanceEnzymeX-ray crystallographyacetyltransferasedrug designfragment based drug discovery