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The role of kinase domain dimerization in EGFR activation

Structure(2025)10.1016/j.str.2025.11.017Source: DataRank Database

The role of kinase domain dimerization in EGFR activation is a research paper published in Structure (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 1.47)OA: greenTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Long Han ORCID,Yuko Tsutsui ORCID,Joshua B. Sheetz ORCID,Kumar D. Ashtekar,Mark A. Lemmon ORCID

Live enrichment

PubMed:41421344 PMC:PMC12731945 OpenAlex:https://openalex.org/W7116060564

National Institute of Dental and Craniofacial Research

Grant: P50-DE030707

National Institute of General Medical Sciences

Grant: R35-GM122485

Frederick National Laboratory for Cancer Research

Grant: 75N91019D00024

National Institutes of Health National Cancer Institute

Grant: R01-CA198164

National Science Foundation

Grant: DGE1122492

NIGMS NIH HHS

Grant: R35 GM122485

NCI NIH HHS

Grant: R01 CA198164

NIDCR NIH HHS

Grant: P50 DE030707

National Institutes of Health

Arnold and Mabel Beckman Foundation

FWCI

1.47

Citation Percentile

0.9%

Citation Trend

2026

greenLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12731945/

publisherhttps://api.elsevier.com/content/article/PII:S0969212625004770?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0969212625004770?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.str.2025.11.017

Fields of Study

HER2/EGFR in Cancer ResearchLung Cancer Treatments and MutationsChronic Myeloid Leukemia TreatmentsErbB ReceptorsHumansProtein MultimerizationCryoelectron MicroscopyModels, MolecularProtein DomainsMutationProtein BindingSignal TransductionEnzyme Activation

MeSH Terms

Protein DomainsEnzyme ActivationHumansModels, MolecularMutationProtein BindingSignal TransductionCryoelectron MicroscopyProtein MultimerizationErbB Receptors

Keywords

Tyrosine kinaseDimerProtein kinase domainEpidermal growth factor receptorKinaseReceptor tyrosine kinaseERBB3IntracellularTyrosineCancerProtein conformationDimerizationReceptor tyrosine kinasesOncogenic MutationGrowth Factor Signaling

Sustainable Development Goals

SDG 0: Good health and well-being

The role of kinase domain dimerization in EGFR activation

FAIR Checklist

Authors (6)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)