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Nanoformulation of BRD4-Degrading PROTAC: Improving Druggability To Target the ‘Undruggable’ MYC in Pancreatic Cancer

Trends in Pharmacological Sciences(2020)10.1016/j.tips.2020.08.008Source: DataRank Database

Nanoformulation of BRD4-Degrading PROTAC: Improving Druggability To Target the ‘Undruggable’ MYC in Pancreatic Cancer is a research paper published in Trends in Pharmacological Sciences (2020). On theSindex it has a DataRank of 0. It has been cited 70 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access70 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 2.76)OA: hybridTopics (58)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (1)

Tamara Minko ORCID

Live enrichment

PubMed:32893006 OpenAlex:https://openalex.org/W3083559812

National Institutes of Health

Grant: 5R01CA209818-03

Tumor-targeted nanoparticle-based delivery system for imaging and treatment of cancer

National Institutes of Health

FWCI

2.76

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S0165614720301899/pdf

publisherhttp://www.cell.com/article/S0165614720301899/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0165614720301899?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0165614720301899?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.tips.2020.08.008

Fields of Study

Protein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsCAR-T cell therapy research0301 basic medicine0303 health sciences03 medical and health sciencesHumansAdaptor Proteins, Signal TransducingCell Cycle ProteinsCell Line, TumorNuclear ProteinsPancreatic NeoplasmsPeptide HydrolasesProteolysisTranscription FactorsUbiquitin-Protein LigasesBromodomain Containing Proteins

MeSH Terms

Bromodomain Containing ProteinsHumansNuclear ProteinsPancreatic NeoplasmsPeptide HydrolasesTranscription FactorsCell Cycle ProteinsUbiquitin-Protein LigasesCell Line, TumorAdaptor Proteins, Signal TransducingProteolysis

Keywords

DruggabilityBRD4CancerCancer researchPancreatic cancerComputational biologyMedicineBioinformaticsBromodomainBiologyGeneticsInternal medicineHistoneDNAGeneMYCPolymeric NanoparticlesProtacArv-825Ubiquitin-Protein LigasesNuclear ProteinsCell Cycle ProteinsPancreatic NeoplasmsBromodomain Containing ProteinsCell Line, TumorProteolysisHumansAdaptor Proteins, Signal TransducingPeptide HydrolasesTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being