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UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer

Translational Oncology(2020)10.1016/j.tranon.2020.100834Source: DataRank Database

UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer is a research paper published in Translational Oncology (2020). On theSindex it has a DataRank of 0. It has been cited 16 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access16 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.21)OA: goldTopics (23)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Sahezeel Awadia ORCID,Amy M. Delaney,Merna Sitto,Carl G. Engelke,Heli Patel ORCID

Live enrichment

PubMed:32688248 PMC:PMC7369648 OpenAlex:https://openalex.org/W3043361713

NCI NIH HHS

Grant: R01 CA240515

NCI NIH HHS

Grant: U01 CA216449

National Institutes of Health

Grant: 3P30CA046592-31S7

Cancer Center Support Grant 2018-2023

National Institutes of Health

Grant: 5R01CA193690-05

Efficacy of PDI inhibitors in glioblastoma

National Institutes of Health

Grant: 5U01CA216449-04

Sensitization to Chemoradiation by Therapeutic Targeting of the DNA Damage Response

National Institutes of Health

FWCI

1.21

Citation Percentile

0.8%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.tranon.2020.100834

publisherhttps://doi.org/10.1016/j.tranon.2020.100834

publisherhttps://api.elsevier.com/content/article/PII:S1936523320303260?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1936523320303260?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32688248

Fields of Study

Endoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyPancreatic function and diabetes0301 basic medicine03 medical and health sciences

Keywords

Unfolded protein responseEndoplasmic reticulumCell biologyDNA damageApoptosisProgrammed cell deathChemistryProtein degradationHomeostasisBiologyBiochemistryDNAPancreatic cancerER stressUae1 InhibitorOriginal articleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being