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Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

Virus Research(2017)10.1016/j.virusres.2016.11.011Source: DataRank Database

Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model is a research paper published in Virus Research (2017). On theSindex it has a DataRank of 0.668. It has been cited 85 times.

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0.668DataRank · unranked

Scored on demand from live citation data

85 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 3.65)OA: hybridTopics (68)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.668

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (10)

Darryl Falzarano ORCID,Jessika C. Zevenhoven-Dobbe,Corrine Beugeling,Craig Fett,Cynthia Martellaro

Live enrichment

PubMed:27840112 OpenAlex:https://openalex.org/W2550848359

Council for Chemical Sciences (CW) of the Netherlands Organization for Scientific Research (NWO)

Grant: 700.57.301

The +RNA virus replication and transcription complex: hijacking membranes to accommodate viral RNA synthesis in the cytoplasm

FWCI

3.65

Citation Percentile

0.9%

Citation Trend

2017

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2025

hybridLicense: cc-by

journalhttps://www.sciencedirect.com/science/article/pii/S0168170216305524/pdf

publisherhttps://www.sciencedirect.com/science/article/pii/S0168170216305524/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0168170216305524?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0168170216305524?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.virusres.2016.11.011

Fields of Study

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesVirus-based gene therapy research0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsAntiviral AgentsCell LineCells, CulturedCoronavirus InfectionsCyclosporineCytopathogenic Effect, ViralDisease Models, AnimalDose-Response Relationship, DrugHumansMiceMiddle East Respiratory Syndrome CoronavirusSevere acute respiratory syndrome-related coronavirusSevere Acute Respiratory SyndromeVirus Replication

MeSH Terms

AnimalsAntiviral AgentsCell LineCells, CulturedCytopathogenic Effect, ViralDisease Models, AnimalDose-Response Relationship, DrugHumansVirus ReplicationCyclosporineCoronavirus InfectionsSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusMiceMiddle East Respiratory Syndrome Coronavirus

Keywords

CoronavirusBiologyMiddle East respiratory syndrome coronavirusVirologyViral replicationCell cultureSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)RibavirinSevere acute respiratory syndrome coronavirusCoronavirus disease 2019 (COVID-19)VirusMicrobiologyGeneticsInfectious disease (medical specialty)MedicineCancer ResearchDose-Response Relationship, DrugSevere Acute Respiratory SyndromeVirus ReplicationAntiviral AgentsArticleCell LineDisease Models, AnimalMiceInfectious DiseasesCytopathogenic Effect, ViralSevere acute respiratory syndrome-related coronavirusCyclosporineAnimalsHumansCoronavirus InfectionsCells, Cultured

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

FAIR Checklist

DataRank Breakdown

Authors (10)

Funding (1 grants)

Impact

Open Access

Topics