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Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2

Cell Genomics(2024)10.1016/j.xgen.2024.100556Source: DataRank Database

Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2 is a research paper published in Cell Genomics (2024). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Open Access18 citations

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Enrichment:Funding (13 grants)Impact (FWCI 2.91)OA: goldTopics (62)IDs (PubMed, PMC, OpenAlex)Annotations (6)SDGs (2)

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Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Bao Khanh Trang ORCID,Christina M. Volpe ORCID,Kieona Cook,Nicole DeBruyne,Jean Ann Maguire

Live enrichment

PubMed:38697123 PMC:PMC11099382 OpenAlex:https://openalex.org/W4396547501

National Institutes of Health

Grant: UL1TR001878

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: UM1 DK126194

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: R01 HD056465

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: F31 HD105404

National Institutes of Health

Grant: 3UL1TR001878-06S1

Institutional Clinical and Translational Science Award

National Institutes of Health

Grant: 5UM1DK126194-04

Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice

National Institutes of Health

Grant: 5F31HD105404-02

Investigating the role of the FAIM2 locus in predisposition to childhood obesity

National Institutes of Health

Grant: 5R01HD056465-08

Genome Wide Association Study for Childhood Obesity

National Center for Advancing Translational Sciences

University of Maryland, Baltimore

Perelman School of Medicine, University of Pennsylvania

University of Pennsylvania Health System

University of Pennsylvania

FWCI

2.91

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.xgen.2024.100556

publisherhttps://doi.org/10.1016/j.xgen.2024.100556

publisherhttps://api.elsevier.com/content/article/PII:S2666979X24001228?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666979X24001228?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38697123

Fields of Study

RNA modifications and cancerAnimal Genetics and ReproductionGenomics and Chromatin Dynamics0301 basic medicine03 medical and health sciencesChildHumans3' Untranslated RegionsAllelesCell DifferentiationChromosomes, Human, Pair 12Genetic Predisposition to DiseaseGenome-Wide Association StudyHuman Embryonic Stem CellsNeuronsPediatric ObesityPolymorphism, Single NucleotideMembrane ProteinsApoptosis Regulatory Proteins

MeSH Terms

Human Embryonic Stem CellsAllelesCell DifferentiationChildChromosomes, Human, Pair 12HumansMembrane ProteinsNeuronsGenetic Predisposition to Disease3' Untranslated RegionsPolymorphism, Single NucleotideApoptosis Regulatory ProteinsGenome-Wide Association StudyPediatric Obesity

Keywords

BiologyAlleleLocus (genetics)GeneticsGeneChromatinEffectorCell biologyHypothalamusObesityStem CellsChildhood ObesityGenome-wide Association StudyNeuron DifferentiationRisk VariantNeuronsPediatric ObesityChromosomes, Human, Pair 12Human Embryonic Stem CellsMembrane ProteinsCell DifferentiationPolymorphism, Single NucleotideArticleHumansGenetic Predisposition to DiseaseChildApoptosis Regulatory Proteins3' Untranslated RegionsAlleles

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 0: Zero hunger

Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2

FAIR Checklist

Authors (17)

Funding (13 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)