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Characterizing the genetic architecture of drug response using gene-context interaction methods

Cell Genomics(2024)10.1016/j.xgen.2024.100722Source: DataRank Database

Characterizing the genetic architecture of drug response using gene-context interaction methods is a research paper published in Cell Genomics (2024). On theSindex it has a DataRank of 0. It has been cited 15 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access15 citations
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Methodology & internals
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring
Enrichment:Funding (20 grants)Impact (FWCI 3.75)OA: goldTopics (81)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)
Findable (1/2)
  • Has DOI
Accessible (1/2)
  • Open Access
Interoperable (0/2)
    Reusable (0/3)

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      Live enrichment

      The Chan Zuckerberg Initiative

      Grant: CZF2019-002449

      National Heart Lung and Blood Institute

      Grant: K25HL157603

      National Institutes of Health

      Grant: 1R01HG011345

      National Institutes of Health

      Grant: U01HG012079

      National Institutes of Health

      Grant: 2R01HG006399

      National Institute of General Medical Sciences

      Grant: R35GM150822

      National Institute of Environmental Health Sciences

      Grant: R01ES029929

      National Institute of Mental Health

      Grant: R01MH125252

      National Institute of Mental Health

      Grant: R01MH122688

      NHGRI NIH HHS

      Grant: R01 HG006399

      NIGMS NIH HHS

      Grant: R35 GM124881

      NIGMS NIH HHS

      Grant: R35 GM153406

      National Institutes of Health

      Grant: 5R01MH125252-05

      SINGLE-CELL MULTI-OMIC APPROACHES TO MECHANISTICALLY CHARACTERIZE PSYCHIATRIC DISORDER RISK LOCI IN THE HUMAN BRAIN

      National Institutes of Health

      Grant: 5K25HL157603-02

      Characterizing individual- and subtype-specific risk factors and treatments in asthma

      National Institutes of Health

      Grant: 2R01HG006399-10A1

      Leveraging functional data to predict disease risk in multi-ethnic populations

      National Institutes of Health

      Grant: 5R35GM150822-02

      Novel statistical genetics methods to unravel polygenic interactions in complex traits

      National Institutes of Health

      Grant: 5R01MH122688-05

      Identifying and quantifying genetic effects on neurodevelopmental trajectories in adolescents

      National Institutes of Health

      Grant: 5R01ES029929-04

      Improved methods for inference of genotype-specific response to environmental toxins

      National Institutes of Health

      Grant: 5U01HG012079-05

      Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency

      National Institutes of Health

      Grant: 5R01HG011345-02

      Genomic Approaches to Population Health in Multi-Ethnic Hospital Systems

      FWCI

      3.75

      Citation Percentile

      0.9%

      Citation Trend

      2025
      2026

      Fields of Study

      Computational Drug Discovery MethodsGenetic Associations and EpidemiologyBioinformatics and Genomic Networks0301 basic medicine03 medical and health sciencesHumansWarfarinMultifactorial InheritanceHydroxymethylglutaryl-CoA Reductase InhibitorsPharmacogeneticsMetforminMethotrexateRetrospective StudiesGlycated HemoglobinMaleFemaleCholesterol, LDLBlood GlucoseGenetic Variation

      MeSH Terms

      Blood GlucoseFemaleGlycated HemoglobinHumansCholesterol, LDLMaleMetforminMethotrexatePharmacogeneticsRetrospective StudiesGenetic VariationWarfarinHydroxymethylglutaryl-CoA Reductase InhibitorsMultifactorial Inheritance

      Keywords

      Context (archaeology)Genetic architectureDrugArchitectureDrug responseComputational biologyGeneBiologyComputer scienceGeneticsPharmacologyGeographyPhenotypeHeritabilityPharmacogenomicsGenetic heterogeneityGenetic TestingPersonalized MedicineGene-environment InteractionsHeteroskedasticityMaleBlood GlucoseMultifactorial Inheritance610ArticleLDL616HumansPrecision MedicineRetrospective StudiesGlycated HemoglobinBiomedical and Clinical SciencesHuman GenomeGene-environment Interactions ; Genetic Heterogeneity ; Genetic Testing ; Heritability ; Heteroskedasticity ; Personalized Medicine ; PharmacogenomicsGenetic VariationPharmacology and Pharmaceutical SciencesCholesterol, LDLBiological SciencesMetforminGood Health and Well BeingCholesterolMethotrexatePharmacogenetics6.1 PharmaceuticalsFemalePatient SafetyWarfarinHydroxymethylglutaryl-CoA Reductase Inhibitors