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A Novel Experimental and Theoretical Method for Estimating Albumin-Mediated Hepatic Uptake Based on the Albumin Binding Fraction in Plasma and Human PK Prediction Using a Physiologically-Based Pharmacokinetic Approach

Journal of Pharmaceutical Sciences(2021)10.1016/j.xphs.2021.01.015Source: DataRank Database

A Novel Experimental and Theoretical Method for Estimating Albumin-Mediated Hepatic Uptake Based on the Albumin Binding Fraction in Plasma and Human PK Prediction Using a Physiologically-Based Pharmacokinetic Approach is a research paper published in Journal of Pharmaceutical Sciences (2021). On theSindex it has a DataRank of 0.363. It has been cited 4 times, with 4 citing works in its 1-hop citation network.

N/A

0.363DataRank · unranked

Scored on demand from live citation data

4 citations · 4 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Impact (FWCI 0.24)OA: closedTopics (35)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 67%Citation Network 33%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

0.121

From 3 citing papers with measurable signal

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Authors (3)

Tomoka Shimada,Kei Mayumi,Yu Egashira

Live enrichment

PubMed:33476657 OpenAlex:https://openalex.org/W3122390182

FWCI

0.24

Citation Percentile

0.5%

Influential Citations

Citation Trend

2021

2023

2024

2025

closedLicense: https://www.elsevier.com/legal/tdmrep-license

publisherhttps://api.elsevier.com/content/article/PII:S0022354921000307?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022354921000307?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.xphs.2021.01.015

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33476657

Fields of Study

Drug Transport and Resistance MechanismsProtein Interaction Studies and Fluorescence AnalysisPharmacogenetics and Drug MetabolismMedicineChemistryAlbuminsBiological TransportHumansLiverModels, BiologicalPharmaceutical PreparationsPharmacokinetics

MeSH Terms

AlbuminsBiological TransportPharmaceutical PreparationsHumansLiverModels, BiologicalPharmacokinetics

Keywords

AlbuminPhysiologically based pharmacokinetic modellingPharmacokineticsChemistryPlasma protein bindingBlood proteinsFree fractionSerum albuminHuman serum albuminPharmacologyChromatographyBiochemistryBiologyDistributionProtein bindingPhysiologically Based Pharmacokinetics

Sustainable Development Goals

SDG 0: Good health and well-being