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A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM

STAR Protocols(2022)10.1016/j.xpro.2022.101732Source: DataRank Database

A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM is a research paper published in STAR Protocols (2022). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (10 grants)Impact (FWCI 1.28)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

David Julius ORCID,Yifan Cheng ORCID,Kaihua Zhang ORCID

Live enrichment

PubMed:36181684 PMC:PMC9530669 OpenAlex:https://openalex.org/W4298151906

National Institutes of Health

Grant: R35NS105038

National Institutes of Health

Grant: S10OD020054

National Institutes of Health

Grant: S10OD021741

NIGMS NIH HHS

Grant: R35 GM140847

National Institutes of Health

Grant: 1R35GM140847-01

Advancing cryo-EM technology to address difficult biological questions

National Institutes of Health

Grant: 5R35NS105038-03

Natural products as probes of the pain pathway

National Institutes of Health

Grant: 1S10OD021741-01

Acquisition of an electron microscope for high-resolution single particle cryo-EM

National Institutes of Health

Grant: 1S10OD020054-01

Linux cluster for near atomic resolution single particle cryo-EM

Howard Hughes Medical Institute

Human Frontier Science Program

FWCI

1.28

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

goldLicense: cc-by

journalhttps://www.sciencedirect.com/science/article/pii/S2666166722006128/pdf

publisherhttps://www.sciencedirect.com/science/article/pii/S2666166722006128/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2666166722006128?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666166722006128?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.xpro.2022.101732

Fields of Study

Advanced Electron Microscopy Techniques and ApplicationsRNA and protein synthesis mechanismsSemiconductor materials and devices0301 basic medicine0303 health sciences03 medical and health sciencesLigand-Gated Ion ChannelsCryoelectron MicroscopyProteinsMolecular ConformationImage Processing, Computer-Assisted

MeSH Terms

Image Processing, Computer-AssistedMolecular ConformationProteinsCryoelectron MicroscopyLigand-Gated Ion Channels

Keywords

Protocol (science)NanodiscComputer scienceParticle (ecology)Ion channelChemistryBiophysicsIonMembrane proteinBiologyReceptorMembraneBiochemistryStructural BiologyCryo-emScience (General)1.1 Normal biological development and functioningImage ProcessingCryoelectron MicroscopyMolecular ConformationProteinsLigand-Gated Ion Channels540530Analytical ChemistryQ1-390Computer-AssistedChemical SciencesPhysical SciencesProtocolImage Processing, Computer-AssistedGeneric health relevance

Sustainable Development Goals

SDG 3: 3. Good health

A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM

FAIR Checklist

Authors (3)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)