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Protocol to generate human liver spheroids to study liver fibrosis induced by metabolic stress

STAR Protocols(2024)10.1016/j.xpro.2024.103111Source: DataRank Database

Protocol to generate human liver spheroids to study liver fibrosis induced by metabolic stress is a research paper published in STAR Protocols (2024). On theSindex it has a DataRank of 0. It has been cited 18 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access18 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)Impact (FWCI 4.28)OA: goldTopics (66)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Wonseok Lee,Xiao Liu ORCID,Haeum Jang,Sadatsugu Sakane ORCID,Raquel Carvalho‐Gontijo Weber

Live enrichment

PubMed:38833372 OpenAlex:https://openalex.org/W4399297950

National Institute of Neurological Disorders and Stroke

Grant: P30NS047101

National Institutes of Health

Grant: P42ES010337

National Institutes of Health

Grant: AA029019

National Institutes of Health

Grant: AA028550

National Institutes of Health

Grant: R01CA285997

National Institutes of Health

Grant: DK099205

National Institutes of Health

Grant: R01DK111866

National Institutes of Health

Grant: R56DK088837

National Institutes of Health

Grant: DK101737

National Institutes of Health

Grant: DK091183

National Institutes of Health

Grant: AA011999

National Institutes of Health

Grant: DK120515

National Institutes of Health

Grant: R44DK115242

Ministry of Education

Grant: RS-2023-00245179

National Institutes of Health

Grant: 5R01DK101737-04

The Role of Portal Fibroblasts in Cholestatic Liver Fibrosis

National Institutes of Health

Grant: 5R44DK115242-03

Development and validation of a novel 3D human in vitro model of nonalcoholic steatohepatitis to be used for novel therapeutic screening and research on disease mechanism.

National Institutes of Health

Grant: 3P50AA011999-12S1

Southern California Research Center for ALPD and Cirrhosis

National Institutes of Health

Grant: 5R01DK111866-03

Fibrocytes regulate liver fibrosis

National Institutes of Health

Grant: 5R01AA028550-04

The role of IL-17 signaling in alcohol-induced HCC

National Institutes of Health

Grant: 5P30NS047101-07

project 1

National Institutes of Health

Grant: 7R01CA285997-03

Collagen fibers and fragments regulate pancreatic cancer metabolism and growth

National Institutes of Health

Grant: 5R01DK099205-05

Inactivation of Hepatic Stellate Cells During Reversal of Liver Fibrosis

National Institutes of Health

Grant: 3P42ES010337-20S1

Harnessing Technological Innovation and Community-Engaged Implementation Science to Optimize COVID-19 Testing for Women and Children in Underserved Communities

National Institutes of Health

Grant: 1R56DK088837-01A1

The Role of Fibrocytes in Liver Fibrosis

National Institutes of Health

Grant: 5P30DK120515-04

San Diego Digestive Diseases Research Center

FWCI

4.28

Citation Percentile

1.0%

Influential Citations

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://ars.els-cdn.com/content/image/1-s2.0-S2666166724002764-fx1_lrg.jpg

GOLDhttps://doi.org/10.1016/j.xpro.2024.103111

publisherhttps://ars.els-cdn.com/content/image/1-s2.0-S2666166724002764-fx1_lrg.jpg

publisherhttps://api.elsevier.com/content/article/PII:S2666166724002764?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666166724002764?httpAccept=text/plain

Fields of Study

Liver physiology and pathologyPancreatic function and diabetesLiver Disease Diagnosis and TreatmentMedicineBiologyEnvironmental Science0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansLiverLiver CirrhosisStress, PhysiologicalSpheroids, CellularCell Culture TechniquesHepatocytes

Keywords

SteatosisInflammationHuman liverSpheroidFibrosisLiver fibrosisMedicineHepatic stellate cellFatty liverBioinformaticsCancer researchBiologyPathologyInternal medicineCell cultureIn vitroBiochemistryLiver CirrhosisScience (General)PhysiologicalorganoidChronic Liver Disease and CirrhosisCell Culture Techniques610612StressOral and gastrointestinalAlcohol Use and HealthSubstance Misusecell isolationQ1-390Stress, PhysiologicalSpheroids, CellularProtocol2.1 Biological and endogenous factorsHumansCancerBiomedical and Clinical Sciences5.2 Cellular and gene therapiesLiver DiseasePharmacology and Pharmaceutical SciencesAlcoholismGood Health and Well BeingLiverChemical SciencesHepatocytesCellularSpheroidsDigestive Diseasesmetabolism

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being