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Protocol for CRISPR-mediated deletion of cis-regulatory element in murine Th17 cells for in vivo assessment of effector function

STAR Protocols(2025)10.1016/j.xpro.2025.103831Source: DataRank Database

Protocol for CRISPR-mediated deletion of cis-regulatory element in murine Th17 cells for in vivo assessment of effector function is a research paper published in STAR Protocols (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (9 grants)Impact (FWCI 0.00)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Hongmin Wu ORCID,Guanpeng Wang,Zuoming Sun ORCID,Xiancai Zhong ORCID

Live enrichment

PubMed:40397576 PMC:PMC12148376 OpenAlex:https://openalex.org/W4410517061

National Institutes of Health

Grant: R21-AI163256

National Institutes of Health National Institute of Allergy and Infectious Diseases

Grant: R01-AI109644

NIAID NIH HHS

Grant: R21 AI163256

NIAID NIH HHS

Grant: R01 AI109644

NCI NIH HHS

Grant: P30 CA016042

NCI NIH HHS

Grant: P30 CA033572

National Institutes of Health

Grant: 5P30CA033572-27

Developmental Funds

National Institutes of Health

Grant: 5R21AI163256-02

Function of TCF-1 in antagonizing malignancy

National Institutes of Health

Grant: 1R01AI109644-01

Differential mechanisms for RORgammat-regulated thymocyte development and Th17 di

FWCI

0.00

Citation Percentile

0.1%

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.xpro.2025.103831

publisherhttps://doi.org/10.1016/j.xpro.2025.103831

publisherhttps://api.elsevier.com/content/article/PII:S2666166725002370?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666166725002370?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40397576

Fields of Study

CRISPR and Genetic EngineeringT-cell and B-cell ImmunologyImmune Cell Function and Interaction0303 health sciences03 medical and health sciencesAnimalsMiceTh17 CellsEncephalomyelitis, Autoimmune, ExperimentalCRISPR-Cas SystemsGene EditingCell DifferentiationRegulatory Sequences, Nucleic AcidClustered Regularly Interspaced Short Palindromic RepeatsMice, Inbred C57BL

MeSH Terms

Gene EditingAnimalsCell DifferentiationEncephalomyelitis, Autoimmune, ExperimentalMice, Inbred C57BLRegulatory Sequences, Nucleic AcidMiceTh17 CellsClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems

Keywords

EffectorCRISPRIn vivoExperimental autoimmune encephalomyelitisFunction (biology)BiologyGeneComputational biologyImmunologyCell biologyGeneticsImmune systemMolecular biologyGene EditingScience (General)Encephalomyelitis, Autoimmune, ExperimentalCell DifferentiationRegulatory Sequences, Nucleic AcidMice, Inbred C57BLQ1-390MiceProtocolAnimalsTh17 CellsClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems

Protocol for CRISPR-mediated deletion of cis-regulatory element in murine Th17 cells for in vivo assessment of effector function

FAIR Checklist

Authors (4)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)