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Protocol for screening inhibitors of the fungal sphingolipid-metabolizing enzyme ceramide synthase

STAR Protocols(2025)10.1016/j.xpro.2025.104078Source: DataRank Database

Protocol for screening inhibitors of the fungal sphingolipid-metabolizing enzyme ceramide synthase is a research paper published in STAR Protocols (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.00)OA: goldTopics (41)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Deveney Dasilva,Nívea Pereira de Sá ORCID,Jeehyun Karen You ORCID,Maurizio Del Poeta ORCID,Andy Zhong

Live enrichment

PubMed:40934076 OpenAlex:https://openalex.org/W4414104492

US Department of Defense

Grant: DODPR190642

National Institutes of Health

Grant: IK6 BX005386

National Institute of Allergy and Infectious Diseases

Grant: AI116420

National Institute of Allergy and Infectious Diseases

Grant: AI184929

National Institute of Allergy and Infectious Diseases

Grant: AI125770

National Institute of Allergy and Infectious Diseases

Grant: AI186554

Stony Brook University

Grant: GZ239

National Institutes of Health

Grant: 5R01AI116420-03

New antifungals targeting the synthesis of fungal sphingolipids

National Institutes of Health

Grant: 1R01AI184929-01A1

Sphingosine kinase and cryptococcal granuloma

National Institutes of Health

Grant: 5R01AI125770-05

Lipid-mediated fungal pathogenesis

FWCI

0.00

Citation Percentile

0.1%

goldLicense: CC BY NC

journalhttps://doi.org/10.1016/j.xpro.2025.104078

publisherhttps://doi.org/10.1016/j.xpro.2025.104078

publisherhttps://api.elsevier.com/content/article/PII:S2666166725004848?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2666166725004848?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40934076

Fields of Study

Sphingolipid Metabolism and SignalingMarine Sponges and Natural ProductsPolysaccharides and Plant Cell Walls0301 basic medicine03 medical and health sciencesOxidoreductasesSphingolipidsSaccharomyces cerevisiaeEnzyme InhibitorsChromatography, High Pressure LiquidAntifungal AgentsMicrosomesDrug Evaluation, Preclinical

MeSH Terms

Antifungal AgentsChromatography, High Pressure LiquidDrug Evaluation, PreclinicalEnzyme InhibitorsMicrosomesOxidoreductasesSaccharomyces cerevisiaeSphingolipids

Keywords

SphingolipidCeramideEnzymeCeramide synthaseIn vitroAntifungalMicrosomeSaccharomyces cerevisiaeLipid signalingSphingolipidsAntifungal AgentsMicrosomesProtocolDrug Evaluation, PreclinicalEnzyme InhibitorsOxidoreductasesChromatography, High Pressure LiquidCell-based AssaysHigh-Throughput ScreeningMicrobiology