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RNAi-Based Gene Therapy Rescues Developmental and Epileptic Encephalopathy in a Genetic Mouse Model

Molecular Therapy(2020)10.1016/j.ymthe.2020.04.007Source: DataRank Database

RNAi-Based Gene Therapy Rescues Developmental and Epileptic Encephalopathy in a Genetic Mouse Model is a research paper published in Molecular Therapy (2020). On theSindex it has a DataRank of 0. It has been cited 36 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access36 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 2.25)OA: hybridTopics (70)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Allison M. Fowler,Megha Sah,Jia Jie Teoh ORCID,Ayla Kanber,Nettie K. Pyne ORCID

Live enrichment

PubMed:32353324 PMC:PMC7335739 OpenAlex:https://openalex.org/W3016490899

NINDS NIH HHS

Grant: R37 NS031348

NIGMS NIH HHS

Grant: T32 GM007754

NIGMS NIH HHS

Grant: T32 GM007088

NIH HHS

Grant: U54 OD020351

NINDS NIH HHS

Grant: F31 NS111808

NINDS NIH HHS

Grant: R01 NS031348

National Institutes of Health

Grant: 5R37NS031348-26

Genetic Determinants of Epilepsy in Murine Systems

National Institutes of Health

Grant: 1F31NS111808-01A1

Modeling gene-specific therapy of intractable childhood epileptic encephalopathy

National Institutes of Health

Grant: 1U54OD020351-01

Project 1 - Epilepsy Project

National Institutes of Health

FWCI

2.25

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S152500162030188X/pdf

publisherhttp://www.cell.com/article/S152500162030188X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S152500162030188X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S152500162030188X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2020.04.007

Fields of Study

Genetics and Neurodevelopmental DisordersRNA regulation and diseaseRNA modifications and cancer03 medical and health sciences0302 clinical medicineAnimalsAnimals, NewbornDependovirusDisease Models, AnimalDynamin IEpileptic SyndromesGenetic TherapyGenetic VectorsHumansInfusions, IntraventricularMiceMicroRNAsRNA InterferenceTreatment Outcome

MeSH Terms

Epileptic SyndromesDependovirusAnimalsAnimals, NewbornDisease Models, AnimalGenetic VectorsHumansGenetic TherapyTreatment OutcomeDynamin IRNA InterferenceMicroRNAsMiceInfusions, Intraventricular

Keywords

RNA interferenceHypotoniaBiologyGenetic enhancementEpilepsyGeneDiseaseBioinformaticsEncephalopathyMedicineGeneticsNeuroscienceInternal medicineGene therapyInfantile spasmsLennox-gastaut SyndromeDeeDynamin-1Dnm1Rna InterferanceAav9Adeno-associated Virus 9Developmental And Epileptic EncephalopathyGenetic VectorsGenetic TherapyDependovirusDisease Models, AnimalMiceMicroRNAsInfusions, IntraventricularTreatment OutcomeAnimals, NewbornAnimalsHumansOriginal ArticleEpileptic SyndromesDynamin I

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being