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CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa

Molecular Therapy(2022)10.1016/j.ymthe.2022.02.010Source: DataRank Database

CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa is a research paper published in Molecular Therapy (2022). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Open Access33 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (28 grants)Impact (FWCI 2.36)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Yi‐Ting Tsai ORCID,I‐Wen Huang,Chia-Hua Cheng ORCID,Chun‐Wei Hsu ORCID,Xuan Cui ORCID

Live enrichment

PubMed:35150888 PMC:PMC9077379 OpenAlex:https://openalex.org/W4211081569

National Institutes of Health

Grant: 5P30CA013696

National Institutes of Health

Grant: 5P30EY019007

National Institutes of Health

Grant: R01EY018213

National Institutes of Health

Grant: R01EY024698

National Institutes of Health

Grant: R01EY026682

National Institutes of Health

Grant: R21AG050437

National Institutes of Health

Grant: R24EY027285

National Institutes of Health

Grant: R24EY028758

National Institutes of Health

Grant: U01 EY030580

National Institutes of Health

Grant: U54OD020351

NEI NIH HHS

Grant: R01 EY033770

NEI NIH HHS

Grant: T32 EY013933

NCI NIH HHS

Grant: P30 CA013696

NEI NIH HHS

Grant: P30 EY019007

National Institutes of Health

Grant: 5U01EY030580-02

Precision genome surgery in autologous stem cell transplant

National Institutes of Health

Grant: 1R24EY027285-01A1

Translational Gene Therapy for CNGB1 Retinitis Pigmentosa

National Institutes of Health

Grant: 5R01EY024698-10

Gene Editing and Silencing in Phototransduction

National Institutes of Health

Grant: 1U54OD020351-01

Project 1 - Epilepsy Project

National Institutes of Health

Grant: 2P30EY019007-06A1

Core Facilities for Vision Research

National Institutes of Health

Grant: 5R21AG050437-02

Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS Cells

National Institutes of Health

Grant: 3P30CA013696-21S1

CANCER CENTER CORE SUPPORT GRANT

National Institutes of Health

Grant: 2R01EY018213-06A1

Defining Barriers to Gene Therapy

National Institutes of Health

Grant: 5R01EY026682-04

Mechanistic Studies on Regenerative Medicine Approaches to Childhood Blindness

Gilbert Family Foundation

Research to Prevent Blindness

Alcon Research Institute

Spark Therapeutics

Abeona Therapeutics

FWCI

2.36

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.ymthe.2022.02.010

publisherhttps://doi.org/10.1016/j.ymthe.2022.02.010

publisherhttps://api.elsevier.com/content/article/PII:S1525001622000934?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1525001622000934?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35150888

Fields of Study

Retinal Development and DisordersCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsDisease Models, AnimalGenes, DominantHumansMutationRetinal DegenerationRetinitis PigmentosaRhodopsinGenetic TherapyMice

Keywords

Retinitis pigmentosaBiologyContext (archaeology)PhenocopyHumanized mouseCRISPRGeneticsGenetic heterogeneityRhodopsinGenetic enhancementRetinal degenerationMutationGeneIn vivoRetinalPhenotypeAAVAdrpAutosomal Dominant DiseaseMutation-independent Gene EditingGenetic TherapyDisease Models, AnimalMiceAnimalsHumansGenes, Dominant

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being