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Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy

Molecular Therapy(2023)10.1016/j.ymthe.2023.03.032Source: DataRank Database

Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy is a research paper published in Molecular Therapy (2023). On theSindex it has a DataRank of 0. It has been cited 27 times.

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0DataRank · unranked

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Open Access27 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 4.47)OA: bronzeTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Mario Mietzsch ORCID,Neeta Khandekar,Arlene D’Silva ORCID,Daniel G. Anderson ORCID,Mawj Mandwie ORCID

Live enrichment

PubMed:37012705 PMC:PMC10362397 OpenAlex:https://openalex.org/W4362523312

National Institutes of Health

Grant: U24 GM129541

Rebecca L Cooper Medical Research Foundation

Grant: PG2019449

NIGMS NIH HHS

Grant: R01 GM082946

National Institutes of Health

National Health and Medical Research Council

Rebecca L Cooper Medical Research Foundation

FWCI

4.47

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

bronzeLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/

journalhttp://www.cell.com/article/S152500162300165X/pdf

publisherhttp://www.cell.com/article/S152500162300165X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S152500162300165X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S152500162300165X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2023.03.032

Fields of Study

Neurogenetic and Muscular Disorders ResearchVirus-based gene therapy researchViral Infections and Immunology Research

MeSH Terms

DependovirusAnimalsAntibodies, MonoclonalCapsidGenetic VectorsHumansInfantGenetic TherapyCryoelectron MicroscopyCapsid ProteinsMice

Keywords

CapsidPolyclonal antibodiesMonoclonal antibodyBiologyAntibodySMA*VirologyGenetic enhancementAdeno-associated virusMolecular biologyVirusGeneImmunologyVector (molecular biology)Recombinant DNAGeneticsAffinityAdeno-associated virus vectorSpinal muscular atrophyNeutralizationRecombinant AavCapsid StructureZolgensmaAnti-Vector Immunity

Sustainable Development Goals

SDG 0: Good health and well-being

Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy

FAIR Checklist

Authors (17)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)