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Dual FKRP/FST gene therapy normalizes ambulation, increases strength, decreases pathology, and amplifies gene expression in LGMDR9 mice

Molecular Therapy(2024)10.1016/j.ymthe.2024.06.028Source: DataRank Database

Dual FKRP/FST gene therapy normalizes ambulation, increases strength, decreases pathology, and amplifies gene expression in LGMDR9 mice is a research paper published in Molecular Therapy (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Scored on demand from live citation data

Open Access2 citations

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hpa refseq

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.31)OA: bronzeTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Deborah A. Zygmunt,Anna Ashbrook ORCID,Macey Bennett,Tatyana A. Vetter ORCID,Paul T. Martin ORCID

Live enrichment

PubMed:38910327 PMC:PMC11405156 OpenAlex:https://openalex.org/W4399925724

NIAMS NIH HHS

Grant: R21 AR079071

National Institutes of Health

Nationwide Children's Hospital

Institut National de la Santé et de la Recherche Médicale

LGMD2I Research Fund

FWCI

0.31

Citation Percentile

0.5%

Citation Trend

2025

bronzeLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/

journalhttp://www.cell.com/article/S1525001624004118/pdf

publisherhttp://www.cell.com/article/S1525001624004118/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1525001624004118?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1525001624004118?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2024.06.028

Fields of Study

Muscle Physiology and DisordersVirus-based gene therapy researchCardiomyopathy and Myosin StudiesAnimalsMiceGenetic TherapyMuscle StrengthDependovirusGenetic VectorsPentosyltransferasesMuscle, SkeletalDisease Models, AnimalGene ExpressionWalkingHumansGene Expression Regulation

MeSH Terms

DependovirusAnimalsDisease Models, AnimalGene Expression RegulationGenetic VectorsHumansPentosyltransferasesGenetic TherapyGene ExpressionWalkingMuscle, SkeletalMiceMuscle Strength

Keywords

Genetic enhancementMuscular dystrophyDiseaseGene expressionGeneMuscle tissueMedicineBiologyCancer researchBioinformaticsInternal medicineGeneticsGlycosylationInflammationAdeno-associated virushypertrophyDystrophinfibrosisDystroglycan