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Structure-guided engineering of CD112 receptor variants for optimized immunotherapy

Molecular Therapy(2025)10.1016/j.ymthe.2025.04.032Source: DataRank Database

Structure-guided engineering of CD112 receptor variants for optimized immunotherapy is a research paper published in Molecular Therapy (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)Impact (FWCI 0.77)OA: greenTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Estefania Julia ORCID,Parismita Kalita ORCID,Charlotte Mason ORCID,Qianqian Ming ORCID,Ansar Lee-Sam

Live enrichment

PubMed:40285356 PMC:PMC12368799 OpenAlex:https://openalex.org/W4409744966

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Grant: R01AI159678

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Grant: G-202206-00524

Moffitt Cancer Center

Grant: P30CA076292

NIH National Institute of General Medical Sciences

Grant: R35GM133482

Rita Allen Foundation

National Institute of Allergy and Infectious Diseases Division of Intramural Research

National Institutes of Health

FWCI

0.77

Citation Percentile

0.7%

Citation Trend

2025

2026

greenLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12368799/

publisherhttps://api.elsevier.com/content/article/PII:S1525001625003119?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1525001625003119?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2025.04.032

Fields of Study

Immunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and InteractionHumansImmunotherapyCell Line, TumorProtein EngineeringProtein BindingReceptors, Chimeric AntigenModels, MolecularLymphocyte ActivationCrystallography, X-RayT-LymphocytesMutationProtein Multimerization

MeSH Terms

Receptors, Chimeric AntigenHumansImmunotherapyLymphocyte ActivationModels, MolecularMutationProtein BindingT-LymphocytesProtein EngineeringCrystallography, X-RayCell Line, TumorProtein Multimerization

Keywords

ImmunotherapyCancer researchCancer immunotherapyReceptorComputational biologyT-cell receptorBiologyImmunologyImmune systemT cellGeneticsProtein engineeringStructural BiologyCheckpoint BlockadeCar T CellsCd112T Cell EngagersCd112r