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Selective inhibition of ERO1α with M6766, a novel small-molecule inhibitor, prevents arterial thrombosis and ischemic stroke in mice

Molecular Therapy(2025)10.1016/j.ymthe.2025.07.033Source: DataRank Database

Selective inhibition of ERO1α with M6766, a novel small-molecule inhibitor, prevents arterial thrombosis and ischemic stroke in mice is a research paper published in Molecular Therapy (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (9 grants)OA: hybridTopics (17)IDs (PubMed, PMC)Annotations (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Kim Js ORCID,Vishwanath Jha ORCID,Gavriel Brown,Jingu Lee ORCID,Radka Bokorová ORCID

Live enrichment

PubMed:40708197 PMC:PMC12393906

National Heart Lung and Blood Institute

Grant: R01HL146559

National Heart Lung and Blood Institute

Grant: R01HL177904

American Heart Association

Grant: POST1011698

American Heart Association

Grant: POST1410518

NIAID NIH HHS

Grant: R01 AI181792

NHLBI NIH HHS

Grant: R01 HL130028

NHLBI NIH HHS

Grant: R01 HL153047

NHLBI NIH HHS

Grant: R01 HL148280

National Institutes of Health

hybridLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.ymthe.2025.07.033

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12393906/

Europe_PMChttps://europepmc.org/articles/PMC12393906

Europe_PMChttps://europepmc.org/articles/PMC12393906?pdf=render

MeSH Terms

Blood PlateletsAnimalsMice, KnockoutHumansMiceThrombosisDisease Models, AnimalEnzyme InhibitorsPlatelet ActivationPlatelet AggregationSmall Molecule LibrariesMolecular Docking SimulationIschemic Stroke

Keywords

Ischemic strokeArterial ThrombosisPlatelet Activation And AggregationEro1α Inhibitors

Selective inhibition of ERO1α with M6766, a novel small-molecule inhibitor, prevents arterial thrombosis and ischemic stroke in mice

FAIR Checklist

Authors (16)

Funding (9 grants)

Open Access

Topics

Annotations (Europe PMC)