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A compact base editor rescues AATD-associated liver and lung disease in mouse models

Molecular Therapy(2025)10.1016/j.ymthe.2025.08.040Source: DataRank Database

A compact base editor rescues AATD-associated liver and lung disease in mouse models is a research paper published in Molecular Therapy (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 1.41)OA: greenTopics (36)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Nathan Bamidele ORCID,Debora Pires-Ferreira,Chunwei Zheng ORCID,April Destefano,Haoyang Cheng ORCID

Live enrichment

PubMed:40883986 OpenAlex:https://openalex.org/W4413787819

National Heart Lung and Blood Institute

Grant: F30HL176024

National Institutes of Health

Grant: P01HL158506

National Institutes of Health

Grant: R01GM150279

National Institutes of Health

Grant: UH3HL147367

National Institutes of Health

Grant: R01CA275945

NIGMS NIH HHS

Grant: R01 GM150273

Friedreich's Ataxia Research Alliance

FWCI

1.41

Citation Percentile

0.8%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12448179/

publisherhttps://api.elsevier.com/content/article/PII:S1525001625006707?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1525001625006707?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2025.08.040

Fields of Study

Peptidase Inhibition and AnalysisAdenosine and Purinergic SignalingCardiovascular Function and Risk FactorsMedicineBiology

MeSH Terms

Gene EditingDependovirusalpha 1-AntitrypsinAnimalsDisease Models, AnimalGenetic VectorsHumansLiver DiseasesLung DiseasesMice, TransgenicMutationGenetic Therapyalpha 1-Antitrypsin DeficiencyMiceCRISPR-Cas Systems

Keywords

Base (topology)Lung diseasePulmonary diseaseLiver diseaseLungDiseaseMedicineImmunologyBiologyInternal medicineMathematicsAAVRare DiseasesMouse LiverGene EditingBase Editing

Sustainable Development Goals

SDG 0: Good health and well-being