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Extracellular vesicle-mediated delivery of CRISPR machinery silences androgen receptor in castration-resistant prostate cancer cells

Molecular Therapy(2025)10.1016/j.ymthe.2025.09.045Source: DataRank Database

Extracellular vesicle-mediated delivery of CRISPR machinery silences androgen receptor in castration-resistant prostate cancer cells is a research paper published in Molecular Therapy (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 1.20)OA: greenTopics (43)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Yongjie Ma ORCID,Raunak Shrestha ORCID,Jingwen Cai ORCID,Yutao Liu ORCID,Peng Liu ORCID

Live enrichment

PubMed:41017153 OpenAlex:https://openalex.org/W4414568921

National Institute of Allergy and Infectious Diseases Division of Intramural Research

Grant: AI171944-01A1

National Institute of Allergy and Infectious Diseases Division of Intramural Research

Grant: R21 AI157831-01A1

National Institutes of Health

Grant: U01 CA225784-01

US Army Medical Command

Grant: W81XWH-22-PCRP-EHDA

NIAID NIH HHS

Grant: R21 AI171944

National Institutes of Health

Grant: DOD W81XWH-22-PCRP-EHDA

NIAID NIH HHS

Grant: R21 AI157831

American Institute for Cancer Research

Georgia Research Alliance

US Army Medical Command

FWCI

1.20

Citation Percentile

0.8%

Citation Trend

2025

2026

greenLicense: https://www.elsevier.com/legal/tdmrep-license

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12925819/

publisherhttps://api.elsevier.com/content/article/PII:S1525001625008160?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1525001625008160?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ymthe.2025.09.045

Fields of Study

Extracellular vesicles in diseaseProstate Cancer Treatment and ResearchHumansMaleReceptors, AndrogenExtracellular VesiclesProstatic Neoplasms, Castration-ResistantCell Line, TumorCRISPR-Cas SystemsGene EditingRNA, Guide, CRISPR-Cas SystemsGene SilencingClustered Regularly Interspaced Short Palindromic RepeatsCell ProliferationCRISPR-Associated Protein 9Ribonucleoproteins

MeSH Terms

Extracellular VesiclesGene EditingCRISPR-Associated Protein 9RNA, Guide, CRISPR-Cas SystemsHumansMaleReceptors, AndrogenRibonucleoproteinsGene SilencingCell Line, TumorCell ProliferationClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsProstatic Neoplasms, Castration-Resistant

Keywords

CRISPRProstate cancerAndrogen receptorGene silencingGenome editingRibonucleoproteinGene deliveryCas9ChromatinExtracellular VesiclesCastration-resistant Prostate CancerChromatin AccessibilityCas9/sgrna Ribonucleoprotein Complex