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Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling

Biochemistry(2020)10.1021/acs.biochem.0c00598Source: DataRank Database

Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling is a research paper published in Biochemistry (2020). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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Enrichment:Funding (5 grants)OA: greenTopics (20)IDs (PubMed, PMC)Annotations (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Linda Yingqi Lin ORCID,Jeffrey O. Zhou ORCID,Emily M. Kibby ORCID,Twan Sia ORCID,Tiara D. Tillis ORCID

Live enrichment

PubMed:33272017 PMC:PMC8407401

National Cancer Institute

Grant: CA226888

National Cancer Institute

Grant: CA226888-S1

NIGMS NIH HHS

Grant: T32 GM133398

NCI NIH HHS

Grant: R01 CA226888

Swarthmore College

greenLicense: https://doi.org/10.15223/policy-029

repositoryhttps://www.biorxiv.org/content/10.1101/2020.07.19.211177v2

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.0c00598

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8407401

MeSH Terms

HumansMelanomaProto-Oncogene Proteins B-rafMAP Kinase Kinase 1Recombinant ProteinsMutagenesis, Site-DirectedMAP Kinase Signaling SystemAllosteric SiteAmino Acid SequencePhosphorylationDrug Resistance, NeoplasmKineticsMutationModels, MolecularProtein Interaction Domains and MotifsStatic ElectricityDrug DiscoveryHEK293 CellsIn Vitro TechniquesProtein Conformation, alpha-Helical

Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling

FAIR Checklist

Authors (20)

Funding (5 grants)

Open Access

Topics

Annotations (Europe PMC)