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New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity

Biochemistry(2023)10.1021/acs.biochem.2c00612Source: DataRank Database

New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity is a research paper published in Biochemistry (2023). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 1.11)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Carrie Hiser ORCID,Fei Li ORCID,Robert M. Hall ORCID,R. Michael Garavito,Shelagh Ferguson‐Miller ORCID

Live enrichment

PubMed:36947867 PMC:PMC10077581 OpenAlex:https://openalex.org/W4353045982

National Cancer Institute

Grant: ACB-12002

National Institutes of Health

Grant: R21 AG057951

National Institute of General Medical Sciences

Grant: AGM-12006

National Institute of General Medical Sciences

Grant: P30GM138396

Argonne National Laboratory

Grant: DE-AC02-06CH11357

National Institutes of Health

Grant: 1R21AG057951-01A1

Defining the role of the Peripheral Benzodiazepine Receptor/translocator protein (TSPO) in inflammatory and stress responses in microglial cellsby comparative analysis

National Institutes of Health

Grant: 1P30GM138396-01

GM/CA@APS: A Macromolecular Crystallography Resource

National Institutes of Health

Grant: 5F32GM012006-03

MOLECULAR GENETIC ANALYSIS OF THE DROSOPHILA 205K MAP

FWCI

1.11

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

hybridLicense: cc-by-nc-nd

journalhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00612

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00612

journalhttps://doi.org/10.1021/acs.biochem.2c00612

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36947867

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10077581

Fields of Study

Porphyrin Metabolism and DisordersNeonatal Health and BiochemistryErythrocyte Function and Pathophysiology0301 basic medicine03 medical and health sciences

MeSH Terms

AlanineBacterial ProteinsBinding SitesCarrier ProteinsHemeLigandsPorphyrinsRhodobacter sphaeroidesProtein Subunits

Keywords

HemeChemistryLigand (biochemistry)Allosteric regulationPorphyrinDimerHemeproteinStereochemistryRhodobacter sphaeroidesBinding siteBiophysicsProtein structureAlanineBiochemistryAmino acidReceptorBiologyEnzymeProtein SubunitsBinding SitesPorphyrinsBacterial ProteinsCarrier ProteinsLigands

Sustainable Development Goals

SDG 0: Life below water