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New Insights into the Mechanism of Action of L-681,217, a Medicinally Promising Polyketide Inhibitor of Bacterial Protein Translation

Biochemistry(2024)10.1021/acs.biochem.4c00541Source: DataRank Database

New Insights into the Mechanism of Action of L-681,217, a Medicinally Promising Polyketide Inhibitor of Bacterial Protein Translation is a research paper published in Biochemistry (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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Linked data & code

gen uniprot pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.64)OA: greenTopics (26)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Rolin A. Aguilar,Heewon Cho ORCID,Thomas M. Privalsky,Lin Liu ORCID,Khanh P. Nguyen ORCID

Live enrichment

PubMed:39576948 PMC:PMC11871046 OpenAlex:https://openalex.org/W4404624774

National Institute of General Medical Sciences

Grant: R35 GM141799

NIH HHS

Grant: S10 OD028697

National Science Foundation Graduate Research Fellowship Program

Stanford University

FWCI

0.64

Citation Percentile

0.7%

Citation Trend

2026

greenLicense: https://doi.org/10.15223/policy-029

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11871046/pdf/nihms-2056557.pdf

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.4c00541

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11871046/

journalhttps://doi.org/10.1021/acs.biochem.4c00541

Fields of Study

Microbial Natural Products and BiosynthesisBacteriophages and microbial interactionsCancer therapeutics and mechanisms

MeSH Terms

Anti-Bacterial AgentsBacterial ProteinsEscherichia coliProtein Synthesis InhibitorsProtein BiosynthesisPolyketides

Keywords

PolyketideEffluxAntibioticsMutantTranslation (biology)EF-TuChloramphenicolProtein biosynthesisAntibiotic resistanceBiotinylationChemistryBiochemistryBiologyEnzymeBiosynthesisMessenger RNAGene

Sustainable Development Goals

SDG 0: Zero hunger

New Insights into the Mechanism of Action of L-681,217, a Medicinally Promising Polyketide Inhibitor of Bacterial Protein Translation

FAIR Checklist

Authors (8)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)