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Inhibitors of SAMHD1 Obtained from Chemical Tethering to the Guanine Antiviral Acyclovir

Biochemistry(2025)10.1021/acs.biochem.4c00854Source: DataRank Database

Inhibitors of SAMHD1 Obtained from Chemical Tethering to the Guanine Antiviral Acyclovir is a research paper published in Biochemistry (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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uniprot pdb doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 1.07)OA: greenTopics (30)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Shridhar Bhat,A. Hasan Howlader ORCID,Mario A. Bianchet ORCID,Yi Liu ORCID,Laura Rovira

Live enrichment

PubMed:39989431 PMC:PMC12035775 OpenAlex:https://openalex.org/W4407881370

National Cancer Institute

Grant: R01 CA233567

National Institute of General Medical Sciences

Grant: GM-131736

NIH HHS

Grant: S10 OD034217

NIGMS NIH HHS

Grant: T32 GM008763

NIGMS NIH HHS

Grant: T32 GM135083

NIGMS NIH HHS

Grant: R35 GM131736

NIGMS NIH HHS

Grant: P30 GM133893

FWCI

1.07

Citation Percentile

0.7%

Citation Trend

2025

2026

greenLicense: https://doi.org/10.15223/policy-029

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12035775/pdf/nihms-2071718.pdf

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.4c00854

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12035775/

journalhttps://doi.org/10.1021/acs.biochem.4c00854

Fields of Study

interferon and immune responsesCytomegalovirus and herpesvirus researchMonoclonal and Polyclonal Antibodies ResearchSAM Domain and HD Domain-Containing Protein 1AcyclovirAntiviral AgentsHumansGuanineAllosteric SiteEnzyme Inhibitors

MeSH Terms

SAM Domain and HD Domain-Containing Protein 1AcyclovirAllosteric SiteAntiviral AgentsEnzyme InhibitorsGuanineHumans

Keywords

TetheringGuanineChemistryAciclovirVirologyStereochemistryBiochemistryCell biologyBiologyVirusNucleotideViral diseaseHerpesviridae

Inhibitors of SAMHD1 Obtained from Chemical Tethering to the Guanine Antiviral Acyclovir

FAIR Checklist

Authors (9)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)