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Segmental Isotope Labeling of the Prion Protein: Identification of a Key Residue for Copper-Mediated Interdomain Structure

ACS Chemical Biology(2025)10.1021/acschembio.5c00336Source: DataRank Database

Segmental Isotope Labeling of the Prion Protein: Identification of a Key Residue for Copper-Mediated Interdomain Structure is a research paper published in ACS Chemical Biology (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 1.15)OA: greenTopics (34)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Kevin Singewald ORCID,Samuel Kaplan ORCID,Eefei Chen ORCID,Glenn L. Millhauser ORCID,Francesca A. Pavlovici ORCID

Live enrichment

PubMed:40704886 OpenAlex:https://openalex.org/W4412632893

NIH Office of the Director

Grant: S10OD024980

National Institute of General Medical Sciences

Grant: K12GM139185

National Institute of General Medical Sciences

Grant: R35GM131781

FWCI

1.15

Citation Percentile

0.8%

Citation Trend

2026

greenLicense: https://doi.org/10.15223/policy-029

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12323768

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acschembio.5c00336

journalhttps://doi.org/10.1021/acschembio.5c00336

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40704886

Fields of Study

Prion Diseases and Protein MisfoldingNeurological diseases and metabolismAmino Acid Enzymes and MetabolismCopperPrion ProteinsAnimalsIsotope LabelingMiceElectron Spin Resonance SpectroscopyProtein DomainsModels, MolecularAminoacyltransferases

MeSH Terms

Prion ProteinsProtein DomainsAnimalsCopperElectron Spin Resonance SpectroscopyIsotope LabelingModels, MolecularAminoacyltransferasesMice

Keywords

Residue (chemistry)CopperChemistryPrion proteinIdentification (biology)BiochemistryIsotopeComputational biologyBiologyMedicinePathologyOrganic chemistryBotany