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Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.5c00117Source: DataRank Database

Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α is a research paper published in ACS Pharmacology & Translational Science (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.85)OA: hybridTopics (17)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

J.C. Nwachukwu ORCID,Kathryn E. Carlson ORCID,Sung Hoon Kim ORCID,Steven R. Angle ORCID,Eric N. Jacobsen ORCID

Live enrichment

PubMed:40810159 PMC:PMC12340639 OpenAlex:https://openalex.org/W4412130764

National Cancer Institute

Grant: R01CA220284

National Cancer Institute

Grant: R01CA275142

National Cancer Institute

Grant: R37CA279341

Breast Cancer Research Foundation

Grant: BCRF-083

Breast Cancer Research Foundation

Grant: BCRF-084

National Institute of General Medical Sciences

Grant: MIRA GM149244

FWCI

1.85

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00117?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00117?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00117

journalhttps://doi.org/10.1021/acsptsci.5c00117

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40810159

Fields of Study

Estrogen and related hormone effectsFree Radicals and AntioxidantsComputational Drug Discovery Methods

Keywords

Estrogen receptorChemistryStereochemistryEstrogenReceptorBiologyBiochemistryEndocrinologyGeneticsComputer modelingNonsteroidal EstrogensBenzestrol IsomersConformationally Flexible EstrogensCongeneric Ligands

Sustainable Development Goals

SDG 0: Zero hunger