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An Assessment of Kinase Selectivity, Enzyme Inhibition Kinetics and in Vitro Activity for Several Bruton Tyrosine Kinase (BTK) Inhibitors

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.5c00412Source: DataRank Database

An Assessment of Kinase Selectivity, Enzyme Inhibition Kinetics and in Vitro Activity for Several Bruton Tyrosine Kinase (BTK) Inhibitors is a research paper published in ACS Pharmacology & Translational Science (2025). On theSindex it has a DataRank of 0.165. It has been cited 2 times.

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0.165DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 2.27)OA: hybridTopics (17)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.165

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (17)

Xiaohu Zhang ORCID,Patricia Alfonso,Patrick J. Morris ORCID,Carleen Klumpp‐Thomas ORCID,Christopher Melani ORCID

Live enrichment

PubMed:41409161 PMC:PMC12707263 OpenAlex:https://openalex.org/W4416329995

National Center for Advancing Translational Sciences

Grant: 1ZIATR000043

National Cancer Institute

Grant: 1ZIABC011008

National Institute of General Medical Sciences

Grant: GM149297

Centro para el Desarrollo Tecnol?gico Industrial

Grant: SoE-20211014

NIGMS NIH HHS

Grant: R35 GM149297

FWCI

2.27

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00412?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00412?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acsptsci.5c00412

journalhttps://doi.org/10.1021/acsptsci.5c00412

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41409161

Fields of Study

Chronic Lymphocytic Leukemia ResearchProtein Degradation and InhibitorsHER2/EGFR in Cancer Research

Keywords

Bruton's tyrosine kinaseKinomeTyrosine kinaseIn vitroKinaseIbrutinibEnzymeCytotoxicityLymphomaBtk InhibitorsB-cell ReceptorCovalent InhibitorsEnzyme Inhibition KineticsKinetic Selectivity