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Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor

Journal of the American Chemical Society(2022)10.1021/jacs.2c10697Source: DataRank Database

Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor is a research paper published in Journal of the American Chemical Society (2022). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Open Access17 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 1.55)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Henry A. Dunn ORCID,Hamid Samareh Afsari ORCID,Henrique S. Seckler ORCID,Max J. Foroutan,Erica Chavez

Live enrichment

PubMed:36475650 PMC:PMC9785046 OpenAlex:https://openalex.org/W4313214255

NCI NIH HHS

Grant: P30 CA060553

National Institute of General Medical Sciences

Grant: R01GM140272-02

NIA NIH HHS

Grant: RF1 AG063903

NIGMS NIH HHS

Grant: R01 GM140272

NIH HHS

Grant: S10 OD011996

NIMH NIH HHS

Grant: F31 MH129114

NIH HHS

Grant: S10 OD026814

NIGMS NIH HHS

Grant: T32 GM105538

NIGMS NIH HHS

Grant: P41 GM108569

National Institute of Mental Health

Grant: F31MH129114-01

NIMH NIH HHS

Grant: R01 MH105482

National Institute on Aging

Grant: RF1AG063903-01

National Institutes of Health

Grant: 1S10OD026814-01

5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

National Institutes of Health

Grant: 1RF1AG063903-01

Defining native proteoform landscape for amyloid-beta in Alzheimers disease

National Institutes of Health

Grant: 1S10OD011996-01

FACSAria SORP Cell Sorter

National Institutes of Health

Grant: 5R01MH105482-04

Orphan Receptors in Regulation of Neuronal G Protein Signaling

National Institutes of Health

Grant: 3P41GM108569-08S1

Expanding Proteoform and Antibody Integration in HuBMAP

National Institutes of Health

Grant: 5P30CA060553-12

The Robert H.Lurie Comprehensive Cancer Center

National Institutes of Health

Grant: 1F31MH129114-01

Characterizing phosphorylation-dependent regulation of metabotropic glutamate receptors by middle-down mass spectrometry

National Institutes of Health

Grant: 5R01GM140272-05

Quantitative analysis of metabotropic glutamate receptor activation and modulation

FWCI

1.55

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

greenLicense: CC BY NC ND

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9785046

journalhttps://doi.org/10.1021/jacs.2c10697

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36475650

Europe_PMChttps://europepmc.org/articles/PMC9785046

Fields of Study

Mass Spectrometry Techniques and ApplicationsReceptor Mechanisms and SignalingAdvanced Proteomics Techniques and Applications0301 basic medicine0303 health sciences03 medical and health sciencesHumansReceptors, G-Protein-CoupledPhosphorylationSignal TransductionLigandsProteomicsMass SpectrometryCarrier Proteins

MeSH Terms

Carrier ProteinsHumansLigandsPhosphorylationMass SpectrometrySignal TransductionProteomicsReceptors, G-Protein-Coupled

Keywords

G protein-coupled receptorPhosphorylationChemistryReceptorMetabotropic glutamate receptor 2Protein phosphorylationMetabotropic receptorSignal transductionAgonistBiochemistryComputational biologyCell biologyBiologyProtein kinase AProteomicsHumansLigandsCarrier ProteinsMass SpectrometryReceptors, G-Protein-Coupled

Sustainable Development Goals

SDG 0: Good health and well-being