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Controlled Self-Immolative Release of β-Lapachone via an Optimized para -Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy

Journal of the American Chemical Society(2025)10.1021/jacs.5c17598Source: DataRank Database

Controlled Self-Immolative Release of β-Lapachone via an Optimized para -Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy is a research paper published in Journal of the American Chemical Society (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 2.75)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Nisita Dutta ORCID,Claudio D. Navo ORCID,Lavinia Dunsmore ORCID,Roman Misteli ORCID,Enrique Gil de Montes ORCID

Live enrichment

PubMed:41392458 PMC:PMC12766730 OpenAlex:https://openalex.org/W4417311787

UK Research and Innovation

Grant: BB/M011194/1

Cambridge Doctoral Training Partnership - 2

Ministerio de Ciencia, Innovación y Universidades

Grant: CEX2021-001136-S

Ministerio de Ciencia, Innovación y Universidades

Grant: PID2021-125946OB-I00

Ministerio de Ciencia, Innovación y Universidades

Grant: PID2024-160774OB-I0

Gates Cambridge Trust

Grant: OPP1144

HORIZON EUROPE Marie Sklodowska-Curie Actions

Grant: 101023887

National Institutes of Health

Grant: ZIA BC 011652

Basinnov Life Sciences

Herchel Smith Fund

National Cancer Institute

NIDUS

FWCI

2.75

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://pubs.acs.org/doi/pdf/10.1021/jacs.5c17598?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/jacs.5c17598?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/jacs.5c17598

journalhttps://doi.org/10.1021/jacs.5c17598

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41392458

Fields of Study

Bioactive Compounds and Antitumor AgentsSynthesis and Biological EvaluationCancer therapeutics and mechanismsNaphthoquinonesHumansPancreatic NeoplasmsProdrugsAntineoplastic AgentsCell Line, TumorDrug LiberationTumor Microenvironment

MeSH Terms

Antineoplastic AgentsHumansNaphthoquinonesPancreatic NeoplasmsProdrugsCell Line, TumorTumor MicroenvironmentDrug Liberation

Keywords

ProdrugPancreatic cancerLinkerMoietyCancer cellCancer therapyCancerEnzymeTumor microenvironment34 Chemical SciencesAntineoplastic AgentsArticlePancreatic NeoplasmsDrug LiberationOrphan DrugRare Diseases5.1 PharmaceuticalsCell Line, TumorHumansProdrugsDigestive DiseasesNaphthoquinones40 Engineering